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二级精神保健中的临床风险评估评分与全因死亡率:南伦敦和莫兹利国民保健信托基金会生物医学研究中心(SLAM BRC)病例登记处。

Clinical risk assessment rating and all-cause mortality in secondary mental healthcare: the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) Case Register.

机构信息

Department of Nursing, College of Medicine, National Taiwan University, Taiwan.

出版信息

Psychol Med. 2012 Aug;42(8):1581-90. doi: 10.1017/S0033291711002698. Epub 2011 Dec 8.

DOI:10.1017/S0033291711002698
PMID:22153124
Abstract

BACKGROUND

Mental disorders are widely recognized to be associated with increased risk of all-cause mortality. However, the extent to which highest-risk groups for mortality overlap with those viewed with highest concern by mental health services is less clear. The aim of the study was to investigate clinical risk assessment ratings for suicide, violence and self-neglect in relation to all-cause mortality among people receiving secondary mental healthcare.

METHOD

A total of 9234 subjects over the age of 15 years were identified from the South London and Maudsley Biomedical Research Centre Case Register who had received a second tier structured risk assessment in the course of their clinical care. A cohort analysis was carried out. Total scores for three risk assessment clusters (suicide, violence and self-neglect) were calculated and Cox regression models used to assess survival from first assessment.

RESULTS

A total of 234 deaths had occurred over an average 9.4-month follow-up period. Mortality was relatively high for the cohort overall in relation to national norms [standardized mortality ratio 3.23, 95% confidence interval (CI) 2.83-3.67] but not in relation to other mental health service users with similar diagnoses. Only the score for the self-neglect cluster predicted mortality [hazard ratio (HR) per unit increase 1.14, 95% CI 1.04-1.24] with null findings for assessed risk of suicide or violence (HRs per unit increase 1.00 and 1.06 respectively).

CONCLUSIONS

Level of clinician-appraised risk of self-neglect, but not of suicide or violence, predicted all-cause mortality among people receiving specific assessment of risk in a secondary mental health service.

摘要

背景

精神障碍被广泛认为与全因死亡率增加有关。然而,死亡率最高的人群与精神卫生服务机构最关注的人群之间有多大程度的重叠尚不清楚。本研究旨在调查接受二级精神卫生保健的人群中,自杀、暴力和自我忽视的临床风险评估评分与全因死亡率的关系。

方法

从南伦敦和莫兹利生物医学研究中心病例登记处确定了 9234 名年龄在 15 岁以上的患者,他们在临床护理过程中接受了二级结构化风险评估。进行了队列分析。计算了三个风险评估群(自杀、暴力和自我忽视)的总分,并使用 Cox 回归模型评估首次评估后的生存情况。

结果

在平均 9.4 个月的随访期间,共有 234 人死亡。与全国标准相比,该队列的总体死亡率相对较高[标准化死亡率比 3.23,95%置信区间(CI)2.83-3.67],但与其他具有类似诊断的精神卫生服务使用者相比则不然。只有自我忽视群的评分预测了死亡率[每单位增加的风险比(HR)1.14,95%CI 1.04-1.24],自杀或暴力风险评估的结果为零[每单位增加的 HR 分别为 1.00 和 1.06]。

结论

在二级精神卫生服务中接受特定风险评估的人群中,临床医生评估的自我忽视风险水平,但不是自杀或暴力风险水平,预测了全因死亡率。

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