Chang Chin-Kuo, Hayes Richard D, Broadbent Matthew, Shetty Hitesh, Su Yu-Ping, Meesters Paul D, Stewart Robert
Global Health Program, College of Public Health, National Taiwan University, Taipei City, Taiwan; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei City, Taiwan; and Department of Psychological Medicine, King's College London, London, UK; South London and Maudsley NHS Foundation Trust, London, UK.
South London and Maudsley NHS Foundation Trust, London, UK; and Department of Psychological Medicine, King's College London, London, UK.
BJPsych Open. 2024 Oct 15;10(6):e178. doi: 10.1192/bjo.2024.765.
Severe mental illness (SMI), which includes schizophrenia, schizoaffective disorder and bipolar disorder, has profound health impacts, even in the elderly.
To evaluate relative risk of hospital admission and length of hospital stay for physical illness in elders with SMI.
To construct a population-based retrospective cohort observed from April 2007 to March 2016, data from a case registry with full but de-identified electronic health records were retrieved for patients of the South London and Maudsley NHS Foundation Trust, the single secondary mental healthcare service provider in south-east London. We compared participants with SMI aged >60 years old with the general population of the same age and residing in the same areas through data linkage by age-, sex- and fiscal-year-standardised admission ratios (SARs) for primary diagnoses at hospital discharge. Furthermore, we compared the duration of hospital stay with an age-, sex- and cause-of-admission-matched random group by linear regression for major causes of admission.
In total, records for 4175 older people with SMI were obtained, relating to 10 342 admission episodes, showing an overall SAR for all physical illnesses of 5.15 (95% CI: 5.05, 5.25). Among the top causes of admission, SARs ranged from 3.87 for circulatory system disorders (ICD-10 codes: I00-I99) to 6.99 for genitourinary system or urinary conditions (N00-N39). Specifically, the diagnostic group of 'symptoms, signs and findings, not elsewhere classified' (R00-R99) had an elevated SAR of 6.56 (95% CI: 6.22, 6.90). Elders with SMI also had significantly longer hospital stays than their counterparts in the general population, especially for digestive system illnesses (K00-K93), after adjusting for confounding.
Poorer overall physical health and specific patterns were identified in elders with SMI.
严重精神疾病(SMI),包括精神分裂症、分裂情感性障碍和双相情感障碍,即使在老年人中也会对健康产生深远影响。
评估患有严重精神疾病的老年人因身体疾病住院的相对风险和住院时间。
构建一个基于人群的回顾性队列,观察时间为2007年4月至2016年3月,从伦敦南部和莫兹利国民保健服务基金会信托基金的病例登记处检索数据,该信托基金是伦敦东南部唯一的二级精神卫生保健服务提供商。我们通过出院时主要诊断的年龄、性别和财政年度标准化入院率(SARs)进行数据链接,将60岁以上患有严重精神疾病的参与者与居住在同一地区的同年龄普通人群进行比较。此外,我们通过对主要入院原因进行线性回归,将住院时间与年龄、性别和入院原因匹配的随机组进行比较。
总共获得了4175名患有严重精神疾病的老年人的记录,涉及10342次入院事件,所有身体疾病的总体标准化入院率为5.15(95%置信区间:5.05,5.25)。在主要入院原因中,标准化入院率从循环系统疾病的3.87(国际疾病分类第10版代码:I00-I99)到泌尿生殖系统或泌尿系统疾病的6.99(N00-N39)不等。具体而言,“未在其他处分类的症状、体征和检查结果”(R00-R99)诊断组的标准化入院率升高至6.56(95%置信区间:6.22,6.90)。在调整混杂因素后,患有严重精神疾病的老年人的住院时间也明显长于普通人群,尤其是消化系统疾病(K00-K93)。
在患有严重精神疾病的老年人中发现了总体身体健康较差和特定模式。