Biomedical Engineering Department, Zhejiang University, Hangzhou Zhejiang 310027, China.
Ultrason Sonochem. 2012 May;19(3):377-82. doi: 10.1016/j.ultsonch.2011.11.010. Epub 2011 Nov 25.
Low intensity ultrasonic therapy is always an important research area of ultrasonic medicine. This review concentrates on low intensity ultrasound enhancing bactericidal action of antibiotics against bacteria in vitro and in vivo, including planktonic bacteria, bacterial biofilms, Chlamydia, and bacteria in implants. These literatures show that low intensity ultrasound alone is not effective in killing bacteria, while the combination of low intensity ultrasound and antibiotics is promising. Low intensity ultrasound facilitating antibiotic treatment is still in its infancy, and still requires a great deal of research in order to develop the technology on medical treatment scale.
低强度超声治疗一直是超声医学的一个重要研究领域。本综述集中讨论了低强度超声增强抗生素对体外和体内细菌的杀菌作用，包括浮游细菌、细菌生物膜、衣原体和植入物中的细菌。这些文献表明，低强度超声单独使用并不能有效杀死细菌，而低强度超声与抗生素联合使用则具有很大的潜力。低强度超声促进抗生素治疗仍处于起步阶段，为了将该技术应用于医疗规模，还需要进行大量的研究。
