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低频超声联合抗生素治疗的综述。

A Review of the Combination Therapy of Low Frequency Ultrasound with Antibiotics.

机构信息

Center of Medicine Clinical Research, Department of Pharmacy, PLA General Hospital, Beijing, China.

出版信息

Biomed Res Int. 2017;2017:2317846. doi: 10.1155/2017/2317846. Epub 2017 Oct 16.

DOI:10.1155/2017/2317846
PMID:29124063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5662814/
Abstract

Single antimicrobial therapy has been unable to resist the global spread of bacterial resistance. Literatures of available and studies were reviewed and the results showed that low frequency ultrasound (LFU) has a promising synergistic bactericidal effect with antibiotics against both planktonic and biofilm bacteria. It also can facilitate the release of antibiotics from medical implants. As a noninvasive and targeted therapy, LFU has great potential in treating bacterial infections. However, more in-depth and detailed studies are still needed before LFU is officially applied as a combination therapy in the field of anti-infective treatment.

摘要

单一的抗菌疗法已经无法抵抗细菌耐药性的全球传播。我们对现有文献和研究进行了回顾，结果表明低频超声（LFU）与抗生素联合使用对浮游菌和生物膜细菌具有有前景的协同杀菌作用。它还可以促进抗生素从医疗植入物中的释放。作为一种非侵入性和靶向治疗方法，LFU 在治疗细菌感染方面具有很大的潜力。然而，在 LF U 正式作为抗感染治疗领域的联合治疗方法应用之前，还需要进行更深入和详细的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3b/5662814/bfed2bce240b/BMRI2017-2317846.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3b/5662814/f33f73b6a2f0/BMRI2017-2317846.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3b/5662814/bfed2bce240b/BMRI2017-2317846.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3b/5662814/f33f73b6a2f0/BMRI2017-2317846.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3b/5662814/bfed2bce240b/BMRI2017-2317846.002.jpg

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