Michels Jorg, Van Der Westhuizen Nicholas, Ross Alison
Vancouver Island Centre, British Columbia Cancer Agency, Victoria, BC;
Can Urol Assoc J. 2011 Dec;5(6):E109-12. doi: 10.5489/cuaj.10164.
Testicular cancer is the most common malignancy in young men with seminomas comprising almost half of all germ cell tumours. Benign ganglioneuromas are rare tumours derived from the sympathetic nervous system. They usually occur in aldolescents and young adults and are predominantly located in the mediastinum and retroperitoneum. We report a case of a patient with synchronous metastatic testicular seminoma with retroperitoneal lymph node involvement and a benign retroperitoneal ganglioneuroma (RGN) which caused diagnostic and management challenges. The patient had a complete response following combination chemotherapy for his seminoma and subsequently underwent complete resection of his ganglioneuroma.
睾丸癌是年轻男性中最常见的恶性肿瘤,其中精原细胞瘤几乎占所有生殖细胞肿瘤的一半。良性神经节神经瘤是起源于交感神经系统的罕见肿瘤。它们通常发生于青少年和青年成人,主要位于纵隔和腹膜后。我们报告一例患者,其同时患有伴腹膜后淋巴结受累的转移性睾丸精原细胞瘤和一个引起诊断及治疗挑战的良性腹膜后神经节神经瘤(RGN)。该患者的精原细胞瘤经联合化疗后完全缓解,随后其神经节神经瘤被完整切除。