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同步性转移性精原细胞瘤和原发性腹膜后神经节细胞瘤:病例报告及文献综述

Synchronous metastatic seminoma and primary retroperitoneal ganglioneuroma: case report and literature review.

作者信息

Michels Jorg, Van Der Westhuizen Nicholas, Ross Alison

机构信息

Vancouver Island Centre, British Columbia Cancer Agency, Victoria, BC;

出版信息

Can Urol Assoc J. 2011 Dec;5(6):E109-12. doi: 10.5489/cuaj.10164.

DOI:10.5489/cuaj.10164
PMID:22154172
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3235184/
Abstract

Testicular cancer is the most common malignancy in young men with seminomas comprising almost half of all germ cell tumours. Benign ganglioneuromas are rare tumours derived from the sympathetic nervous system. They usually occur in aldolescents and young adults and are predominantly located in the mediastinum and retroperitoneum. We report a case of a patient with synchronous metastatic testicular seminoma with retroperitoneal lymph node involvement and a benign retroperitoneal ganglioneuroma (RGN) which caused diagnostic and management challenges. The patient had a complete response following combination chemotherapy for his seminoma and subsequently underwent complete resection of his ganglioneuroma.

摘要

睾丸癌是年轻男性中最常见的恶性肿瘤,其中精原细胞瘤几乎占所有生殖细胞肿瘤的一半。良性神经节神经瘤是起源于交感神经系统的罕见肿瘤。它们通常发生于青少年和青年成人,主要位于纵隔和腹膜后。我们报告一例患者,其同时患有伴腹膜后淋巴结受累的转移性睾丸精原细胞瘤和一个引起诊断及治疗挑战的良性腹膜后神经节神经瘤(RGN)。该患者的精原细胞瘤经联合化疗后完全缓解,随后其神经节神经瘤被完整切除。

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AACE Clin Case Rep. 2019 Jun 26;5(5):e321-e325. doi: 10.4158/ACCR-2019-0251. eCollection 2019 Sep-Oct.
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Post-orchidectomy retroperitoneal seminoma: A case report.睾丸切除术后腹膜后精原细胞瘤:一例报告。
Oncol Lett. 2013 Apr;5(4):1240-1242. doi: 10.3892/ol.2013.1152. Epub 2013 Jan 23.

本文引用的文献

1
Retroperitoneal ganglioneuroma in an adult patient: a case report and literature review of the last decade.一名成年患者的腹膜后神经节细胞瘤:病例报告及过去十年的文献综述
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Massive retroperitoneal ganglioneuroma presenting with small bowel obstruction 18 years following initial diagnosis.初次诊断18年后出现小肠梗阻的巨大腹膜后神经节细胞瘤。
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European consensus on diagnosis and treatment of germ cell cancer: a report of the European Germ Cell Cancer Consensus Group (EGCCCG).欧洲生殖细胞癌诊断与治疗共识:欧洲生殖细胞癌共识小组(EGCCCG)报告
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Metabolic activity and clinical features of primary ganglioneuromas.原发性神经节细胞瘤的代谢活性与临床特征
Cancer. 2001 May 15;91(10):1905-13. doi: 10.1002/1097-0142(20010515)91:10<1905::aid-cncr1213>3.0.co;2-4.
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[Positron emission tomography with [18 F]-2-fluoro-2-deoxy-D-glucose (18FDG-PET) in diagnosis of retroperitoneal lymph node metastases of testicular tumors].[¹⁸F]-2-氟-2-脱氧-D-葡萄糖正电子发射断层扫描(¹⁸FDG-PET)在睾丸肿瘤腹膜后淋巴结转移诊断中的应用
Urologe A. 1998 Nov;37(6):609-20. doi: 10.1007/s001200050223.
7
Aspiration cytology and immunohistochemistry of a pheochromocytoma-ganglioneuroma of the adrenal gland.肾上腺嗜铬细胞瘤-神经节细胞瘤的针吸细胞学检查及免疫组织化学检查
Acta Cytol. 1987 Jan-Feb;31(1):33-9.