Dąbrowska-Thing Agnieszka, Rogowski Wojciech, Pacho Ryszard, Nawrocka-Laskus Ewa, Nitek Żaneta
Department of Diagnostic Imaging, Gruca Orthopedic and Trauma Teaching Hospital, Centre of Postgraduate Education, Otwock, Poland.
Department of Urology and Oncological Urology, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland.
Pol J Radiol. 2017 May 25;82:283-286. doi: 10.12659/PJR.899633. eCollection 2017.
Ganglioneuroma (GN) is a rare benign tumor arising from the neural crest cells. The reported incidence of GN is one per million population. As a primary retroperitoneal tumor, it constitutes only a small percentage of 0.72 to 1.6%. GN can arise or as a result of maturation of a neuroblastoma either spontaneously or after chemotherapy. The most common location is the posterior paraspinal mediastinum, retroperitoneum, neck and adrenal gland. However, GN can potentially occur anywhere along the peripheral autonomic ganglion sites. Most ganglioneuromas are asymptomatic and found incidentally.
We present a case of retroperitoneal ganglioneuroma that mimicked renal mass on imaging. The tumor was incidentally discovered during an abdominal ultrasound examination 43-year-old male patient without clinical symptoms. Complete surgical resection was subsequently performed and histopathological examination of the retroperitoneal mass revealed GN.
Retroperitoneal ganglioneuroma is a rare bening tumor, generally asymptomatic, which grows slowly, and appears large when it is identified. Preoperative diagnosis can be challenging, particularly in asymptomatic case. Histopathological examination is currently the mainstay of diagnosis. In the case presented herein GN stricktly adjoined to the left kidney mimicking renal mass.
神经节神经瘤（GN）是一种起源于神经嵴细胞的罕见良性肿瘤。据报道，GN的发病率为百万分之一。作为一种原发性腹膜后肿瘤，它仅占0.72%至1.6%的一小部分。GN可自发出现，也可由神经母细胞瘤在化疗后成熟而产生。最常见的部位是后纵隔脊柱旁、腹膜后、颈部和肾上腺。然而，GN可能发生在沿周围自主神经节的任何部位。大多数神经节神经瘤无症状，多为偶然发现。
我们报告一例腹膜后神经节神经瘤，其在影像学上酷似肾脏肿块。该肿瘤是在一名43岁无症状男性患者的腹部超声检查中偶然发现的。随后进行了完整的手术切除，腹膜后肿块的组织病理学检查显示为神经节神经瘤。
腹膜后神经节神经瘤是一种罕见的良性肿瘤，通常无症状，生长缓慢，发现时体积较大。术前诊断具有挑战性，尤其是在无症状的情况下。目前组织病理学检查是诊断的主要依据。在本文所述病例中，神经节神经瘤与左肾紧密相邻，酷似肾脏肿块。
