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印度传统保健系统中的免疫调节剂述评。

A review of immunomodulators in the Indian traditional health care system.

机构信息

Department of Pharmaceutical Sciences, University of Kashmir, 190006 India.

出版信息

J Microbiol Immunol Infect. 2012 Jun;45(3):165-84. doi: 10.1016/j.jmii.2011.09.030. Epub 2011 Dec 11.

DOI:10.1016/j.jmii.2011.09.030
PMID:22154993
Abstract

Some of the medicinal plants valued in Ayurvedic Rasayana for their therapeutic potential have been scientifically investigated with promising results. A number of plant-based principles have been isolated with potential immunomodulatory activity that can explain and justify their use in traditional medicine in the past and can form the basis for further research in the future as well. The aim of this review is to highlight results of research done on immunomodulators of plant origin. The selection of papers was made using the most relevant databases for the biomedical sciences on the basis of their ethnopharmacological use. Many plants and some phytoconstituents responsible for immunomodulation have been explained. The review also discusses biological screening methods for various plant drugs that focus on revealing the mechanism involved in immunomodulation. This work shall hopefully encourage researchers to undertake further work on medicinal plants with potential immunomodulatory activity.

摘要

一些在印度阿育吠陀医学 Rasayana 中因其治疗潜力而受到重视的药用植物已经过科学研究,取得了有希望的结果。已经分离出一些具有潜在免疫调节活性的植物性原则,这些原则可以解释和证明它们在过去传统医学中的应用,并为未来的进一步研究提供基础。本综述的目的是强调对植物来源的免疫调节剂的研究结果。论文的选择是根据其民族药理学用途,使用最相关的生物医学科学数据库进行的。已经解释了许多负责免疫调节的植物和一些植物成分。该综述还讨论了各种植物药物的生物筛选方法,这些方法侧重于揭示免疫调节中涉及的机制。这项工作有望鼓励研究人员对具有潜在免疫调节活性的药用植物进行进一步研究。

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