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听觉处理中的皮质高伽马反应。

Cortical high-gamma responses in auditory processing.

作者信息

Cervenka Mackenzie C, Nagle Stephanie, Boatman-Reich Dana

机构信息

Johns Hopkins School of Medicine, Baltimore, MD, USA.

出版信息

Am J Audiol. 2011 Dec;20(2):171-80. doi: 10.1044/1059-0889(2011/10-0036).

Abstract

PURPOSE

This tutorial provides an introduction to cortical auditory spectral responses, focusing on event-related activity in the high-gamma frequencies (60-150 Hz), their recent emergence in neuroscience research, and potential clinical applications.

METHOD

Auditory high-gamma responses are described and compared with traditional cortical evoked responses, including the auditory evoked N1 response. Methods for acquiring and analyzing spectral responses, including time-frequency analyses, are discussed and contrasted with more familiar time-domain averaging approaches. Four cases are presented illustrating high-gamma response patterns associated with normal and impaired auditory processing.

CONCLUSIONS

Cortical auditory high-gamma responses may provide a useful clinical measure of auditory processing.

摘要

目的

本教程介绍皮质听觉频谱反应,重点关注高伽马频率(60 - 150赫兹)下的事件相关活动、它们在神经科学研究中的最新出现情况以及潜在的临床应用。

方法

描述听觉高伽马反应,并将其与传统皮质诱发反应(包括听觉诱发N1反应)进行比较。讨论获取和分析频谱反应的方法,包括时频分析,并将其与更常见的时域平均方法进行对比。展示四个案例,说明与正常和受损听觉处理相关的高伽马反应模式。

结论

皮质听觉高伽马反应可能为听觉处理提供一种有用的临床测量方法。

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