PKC-ing is believing: targeting protein kinase C in heart failure.
作者信息
Belmonte Stephen L, Blaxall Burns C
出版信息
Circ Res. 2011 Dec 9;109(12):1320-2. doi: 10.1161/CIRCRESAHA.111.259358.
Abstract
摘要
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PKC-ing is believing: targeting protein kinase C in heart failure.蛋白激酶C可信：心力衰竭中靶向蛋白激酶C
Circ Res. 2011 Dec 9;109(12):1320-2. doi: 10.1161/CIRCRESAHA.111.259358.
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Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury.PKCα/β 抑制作用（ruboxistaurin）拮抗心肌梗死后猪的心衰。
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Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach.蛋白激酶Cα而非蛋白激酶Cβ或蛋白激酶Cγ调节收缩性和心力衰竭易感性：鲁比前列酮作为一种新型治疗方法的意义。
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Can protein kinase C beta-selective inhibitor, ruboxistaurin, stop vascular complications in diabetic patients?蛋白激酶Cβ选择性抑制剂鲁伯斯塔林能否阻止糖尿病患者的血管并发症？
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New hope for the treatment of diabetic complications.糖尿病并发症治疗的新希望。
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[Protein kinase C beta-Inhibitor ruboxistaurin].[蛋白激酶Cβ抑制剂鲁比前列酮]
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Ruboxistaurin mesilate hydrate for diabetic retinopathy.甲磺酸盐鲁比前列酮水合物用于治疗糖尿病性视网膜病变。
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Ruboxistaurin for diabetic retinopathy.鲁比前列酮用于治疗糖尿病性视网膜病变。
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PKC-B inhibition: a new therapeutic approach for diabetic complications?蛋白激酶C-β抑制：糖尿病并发症的一种新治疗方法？
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Protein kinase C inhibition and diabetic retinopathy: a shot in the dark at translational research.蛋白激酶C抑制与糖尿病视网膜病变：转化研究中的一次盲目尝试。
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Long QT2 mutation on the Kv11.1 ion channel inhibits current activity by ablating a protein kinase Cα consensus site.Kv11.1 离子通道上的长 QT2 突变通过消除蛋白激酶 Cα 共有位点来抑制电流活性。
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