McColgin S W, Hampton H L, McCaul J F, Howard P R, Andrew M E, Morrison J C
Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson.
Obstet Gynecol. 1990 Oct;76(4):678-80.
Membrane stripping has been used clinically for many years but has not been well studied. An investigation was undertaken to determine whether weekly membrane stripping beginning at 38 weeks could safely reduce post-term pregnancies. One hundred eighty patients with firm gestational dates were randomized to either a treatment or control group. Control subjects received a gentle cervicovaginal examination each week to assess Bishop scores, whereas the treatment group also underwent weekly stripping of membranes. Women who received treatment had earlier delivery (mean +/- SEM 8.60 +/- 0.74 versus 15.14 +/- 0.83 days; P less than .0001) and fewer post-term deliveries than those in the control group (three versus 14; P less than .004). The reduction of post-term pregnancies was most notable in nulliparous women with unfavorable Bishop scores. Complications were similar in both groups. Membrane stripping was safe and was associated with earlier delivery and a decreased incidence of post-term gestation.
胎膜剥离术已在临床上应用多年，但尚未得到充分研究。开展了一项调查，以确定从38周开始每周进行胎膜剥离术是否能安全减少过期妊娠。180名孕周确定的患者被随机分为治疗组或对照组。对照组受试者每周接受一次轻柔的宫颈阴道检查以评估Bishop评分，而治疗组还每周进行胎膜剥离术。接受治疗的女性分娩时间更早（平均±标准误8.60±0.74天对15.14±0.83天；P＜0.0001），过期分娩的人数也比对照组少（3例对14例；P＜0.004）。在Bishop评分不利的初产妇中，过期妊娠的减少最为显著。两组的并发症相似。胎膜剥离术是安全的，并且与更早分娩以及过期妊娠发生率降低相关。
