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过氧化氢——过去的一个聚会小把戏?

Hydrogen peroxide--a party trick from the past?

作者信息

Reid C J, Alcock M, Penn D

机构信息

Department of Anaesthesia, Launceston General Hospital, Launceston, Tasmania, Australia.

出版信息

Anaesth Intensive Care. 2011 Nov;39(6):1004-8. doi: 10.1177/0310057X1103900604.

DOI:10.1177/0310057X1103900604
PMID:22165350
Abstract

Hydrogen peroxide solutions are found in almost every operating theatre and are used by many surgical specialties, often with little knowledge of their inherent risk. We reviewed the literature and evidence related to the use of hydrogen peroxide in surgery. We found little evidence supporting the use of hydrogen peroxide solutions intraoperatively, a large number of reports of sometimes-fatal oxygen embolism and other evidence of tissue toxicity. We conclude that the use of hydrogen peroxide as an antiseptic has no direct benefit, but is associated with significant risk, and therefore should be reconsidered.

摘要

几乎每个手术室都有过氧化氢溶液,许多外科专科都在使用,而他们往往对其潜在风险知之甚少。我们回顾了与手术中使用过氧化氢相关的文献和证据。我们发现几乎没有证据支持术中使用过氧化氢溶液,却有大量关于有时会致命的氧气栓塞的报告以及其他组织毒性的证据。我们得出结论,使用过氧化氢作为消毒剂没有直接益处,反而伴有重大风险,因此应重新考虑。

相似文献

1
Hydrogen peroxide--a party trick from the past?过氧化氢——过去的一个聚会小把戏?
Anaesth Intensive Care. 2011 Nov;39(6):1004-8. doi: 10.1177/0310057X1103900604.
2
[Oxygen embolism after intraoperative use of hydrogen peroxide].[术中使用过氧化氢后发生氧气栓塞]
Masui. 2002 Dec;51(12):1368-70.
3
Oxygen embolism due to hydrogen peroxide irrigation during cervical spinal surgery.颈椎手术中过氧化氢冲洗导致的氧栓塞
Can J Anaesth. 1995 Mar;42(3):231-3. doi: 10.1007/BF03010684.
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Near-fatal systemic oxygen embolism due to wound irrigation with hydrogen peroxide.过氧化氢伤口冲洗致近乎致命的全身性氧栓塞
Postgrad Med J. 1982 Jul;58(681):448-50. doi: 10.1136/pgmj.58.681.448.
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[Oxygen embolism after use of hydrogen peroxide in thoracic surgery].[胸外科手术中使用过氧化氢后发生氧栓塞]
Schweiz Med Wochenschr. 1997 Nov 8;127(45):1871-4.
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Oxygen venous embolism after the use of hydrogen peroxide during lumbar discectomy.腰椎间盘切除术中使用过氧化氢后发生的氧静脉栓塞。
Can J Anaesth. 1997 Apr;44(4):410-3. doi: 10.1007/BF03014463.
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[Severe air embolism after surgical irrigation with hydrogen peroxide].[过氧化氢手术冲洗后发生严重空气栓塞]
Presse Med. 1999 Jan 30;28(4):173-5.
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Oxygen embolism after hydrogen peroxide irrigation of a vulvar abscess.过氧化氢冲洗外阴脓肿后发生氧栓塞
Br J Anaesth. 2002 Apr;88(4):597-9. doi: 10.1093/bja/88.4.597.
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Gas embolism produced by hydrogen peroxide abscess irrigation in an infant.过氧化氢用于婴儿脓肿冲洗引发气体栓塞
Anaesth Intensive Care. 1999 Aug;27(4):418-20. doi: 10.1177/0310057X9902700417.
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Gas embolism produced by hydrogen peroxide irrigation of an anal fistula during anesthesia.
Anesthesiology. 1985 Sep;63(3):316-7. doi: 10.1097/00000542-198509000-00013.

引用本文的文献

1
Oxygen embolism caused by accidental subcutaneous injection of hydrogen peroxide during orthopedic surgery: A case report.骨科手术中意外皮下注射过氧化氢导致的氧栓塞:一例报告。
Medicine (Baltimore). 2017 Oct;96(43):e8342. doi: 10.1097/MD.0000000000008342.