Krzemiński Tadeusz Faustyn, Gilowski Łukasz, Wiench Rafał, Płocica Iwona, Kondzielnik Piotr, Sielańczyk Andrzej
Department of Pharmacology, Medical University of Silesia, Jordana 19, 41-808 Zabrze, Poland.
Am J Dent. 2011 Oct;24(5):305-9.
To compare the efficacy of maxillary infiltration anesthesia with 0.5% plain ropivacaine or 2% lidocaine with epinephrine 1:100,000.
60 volunteers received 1.8 ml of the anesthetic for infiltration anesthesia of maxillary central and lateral incisors and canine teeth. The onset time and duration of pulp anesthesia were assessed with an electric pulp tester. The duration time of numbness of the upper lip was also monitored. Blood pressure and heart rate were measured before and after administration of the solution.
The efficacy of anesthesia of the lateral and central incisors was 100% for both anesthetics. There were small insignificant differences in effectiveness of canine pulp anesthesia. The mean onset time was significantly shorter for ropivacaine--2.2 minutes vs. 5.1 for lidocaine. Ropivacaine also had a significantly longer duration of action--mean time 79.2 minutes. Ropivacaine caused statistically significant increases in blood pressure and heart rate.
比较0.5%普通罗哌卡因与2%利多卡因加1:100,000肾上腺素在上颌浸润麻醉中的效果。
60名志愿者接受1.8毫升麻醉剂用于上颌中切牙、侧切牙和尖牙的浸润麻醉。用电活力测试仪评估牙髓麻醉的起效时间和持续时间。同时监测上唇麻木的持续时间。在溶液给药前后测量血压和心率。
两种麻醉剂对侧切牙和中切牙的麻醉效果均为100%。在尖牙髓麻醉效果方面存在微小的无显著差异。罗哌卡因的平均起效时间明显更短——2.2分钟，而利多卡因为5.1分钟。罗哌卡因的作用持续时间也明显更长——平均时间为79.2分钟。罗哌卡因导致血压和心率在统计学上显著升高。
