Liu Kemin, Ye Qing, Zhao Yichen, Zhao Cheng, Song Li, Liu Yang, Bai Chen, Han Jie, Wang Shengyu, Wang Jiangang
Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, 100069 Beijing, China.
Department of Ultrasound, Beijing Anzhen Hospital, Capital Medical University, 100069 Beijing, China.
Rev Cardiovasc Med. 2024 Apr 17;25(4):146. doi: 10.31083/j.rcm2504146. eCollection 2024 Apr.
Mitral valve repair (MVr) is an effective treatment for degenerative mitral regurgitation (DMR).And the outcomes and repair rates for posterior leaflet prolapse (PLP), anterior leaflet prolapse (ALP), and bileaflet prolapse (BLP) vary. This study aimed to compare the outcomes of mitral valve repair for patients with PLP, ALP, and BLP.
From 2010 to 2019, 1192 patients with degenerative mitral valve regurgitation underwent surgery at our hospital. And 1069 patients were identified. The average age of all patients was (54.74 12.17) years old for all patients. 273 patients (25.5%) had ALP, 148 patients (13.8%) had BLP, and 648 patients (60.6%) had PLP. All patients were followed up for an average duration of 5.1 years. We compared the outcomes of patients with ALP, PLP, and BLP.
Patients with ALP were the youngest of the 3 groups and had the highest prevalence of atrial fibrillation. Patients with PLP had the highest prevalence of hypertension, whereas patients with BLP and ALP had larger left ventricular end-diastolic and left ventricular end-systolic diameters. ALP and BLP repairs had a longer cardiopulmonary bypass and aortic cross-clamp time.10 patients dead in-hospital, 5 patients had PLP, 3 had ALP, and 2 had BLP. The 10-year survival cumulative incidences of reoperation among ALP, BLP, and PLP repairs were not significantly different. ALP repair still had higher cumulative incidences of recurrent mitral regurgitation (MR) compared to PLP.
The rates of long-term survival and freedom from reoperation were not significantly different among patients with ALP, BLP, and PLP. ALP repair has higher cumulative incidences of recurrent MR compared to PLP.
二尖瓣修复术(MVr)是治疗退行性二尖瓣反流(DMR)的有效方法。后叶脱垂(PLP)、前叶脱垂(ALP)和双叶脱垂(BLP)的手术结果和修复率各不相同。本研究旨在比较PLP、ALP和BLP患者二尖瓣修复的结果。
2010年至2019年,我院1192例退行性二尖瓣反流患者接受了手术。共纳入1069例患者。所有患者的平均年龄为(54.74±12.17)岁。273例患者(25.5%)为ALP,148例患者(13.8%)为BLP,648例患者(60.6%)为PLP。所有患者平均随访5.1年。我们比较了ALP、PLP和BLP患者的手术结果。
ALP患者是三组中最年轻的,房颤患病率最高。PLP患者高血压患病率最高,而BLP和ALP患者的左心室舒张末期和收缩末期直径更大。ALP和BLP修复的体外循环和主动脉阻断时间更长。10例患者住院死亡,5例为PLP,3例为ALP,2例为BLP。ALP、BLP和PLP修复术后再次手术的10年生存累积发生率无显著差异。与PLP相比,ALP修复术后二尖瓣反流(MR)复发的累积发生率仍然较高。
ALP、BLP和PLP患者的长期生存率和再次手术率无显著差异。与PLP相比,ALP修复术后MR复发的累积发生率更高。