Middleton S J, Jacyna M, McClaren D, Robinson R, Thomas H C
St. Mary's Hospital, Paddington, London, UK.
Postgrad Med J. 1990 Aug;66(778):657-8. doi: 10.1136/pgmj.66.778.657.
Severe potassium permanganate poisoning (more than 10 g of potassium permanganate) is invariably associated with massive systemic upset and death. Multiple organ damage has been recognized as an inevitable consequence of such an overdose, although pancreatitis has not been previously reported. Death due to cardiovascular collapse and profound hypotension is a common end point in those who reach hospital, but the pathogenesis is uncertain. We report a case of haemorrhagic pancreatitis following an overdose of potassium permanganate and suggest that this complication may be an unrecognized factor contributing to the extremely high mortality rate associated with this condition.
重度高锰酸钾中毒(超过10克高锰酸钾)必然会导致严重的全身不适和死亡。尽管此前未曾有过胰腺炎的报道,但多器官损伤已被认为是这种过量摄入的必然结果。因心血管衰竭和严重低血压导致的死亡是那些被送往医院患者的常见结局,但其发病机制尚不确定。我们报告一例过量服用高锰酸钾后发生出血性胰腺炎的病例,并表明这种并发症可能是导致与该病症相关的极高死亡率的一个未被认识到的因素。