感觉间注意节律性听觉和视觉输入时的振荡感觉选择机制:一项人类脑电皮质图研究。
Oscillatory sensory selection mechanisms during intersensory attention to rhythmic auditory and visual inputs: a human electrocorticographic investigation.
机构信息
The Cognitive Neurophysiology Laboratory, Nathan S. Kline Institute for Psychiatric Research, Program in Cognitive Neuroscience and Schizophrenia, Orangeburg, New York 10962, USA.
出版信息
J Neurosci. 2011 Dec 14;31(50):18556-67. doi: 10.1523/JNEUROSCI.2164-11.2011.
Oscillatory entrainment mechanisms are invoked during attentional processing of rhythmically occurring stimuli, whereby their phase alignment regulates the excitability state of neurons coding for anticipated inputs. These mechanisms have been examined in the delta band (1-3 Hz), where entrainment frequency matches the stimulation rate. Here, we investigated entrainment for subdelta rhythmic stimulation, recording from intracranial electrodes over human auditory cortex during an intersensory audiovisual task. Audiovisual stimuli were presented at 0.67 Hz while participants detected targets within one sensory stream and ignored the other. It was found that entrainment operated at twice the stimulation rate (1.33 Hz), and this was reflected by higher amplitude values in the FFT spectrum, cyclic modulation of alpha-amplitude, and phase-amplitude coupling between delta phase and alpha power. In addition, we found that alpha-amplitude was relatively increased in auditory cortex coincident with to-be-ignored auditory stimuli during attention to vision. Thus, the data suggest that entrainment mechanisms operate within a delimited passband such that for subdelta task rhythms, oscillatory harmonics are invoked. The phase of these delta-entrained oscillations modulates alpha-band power. This may in turn increase or decrease responsiveness to relevant and irrelevant stimuli, respectively.
在对周期性出现的刺激进行注意力处理时,会调用震荡同步机制,通过这种机制,其相位对准调节了编码预期输入的神经元的兴奋性状态。这些机制在 delta 频段(1-3 Hz)中进行了研究,其中同步频率与刺激率匹配。在这里,我们在人类听觉皮层的颅内电极上记录了跨感觉视听任务期间的 subdelta 节律性刺激,研究了同步现象。视听刺激以 0.67 Hz 的频率呈现,而参与者在一个感觉流中检测目标,忽略另一个感觉流。结果发现,同步作用于刺激率的两倍(1.33 Hz),这反映在 FFT 谱中的更高振幅值、alpha 振幅的周期性调制以及 delta 相位和 alpha 功率之间的相位-振幅耦合上。此外,我们发现,在注意视觉时,与要忽略的听觉刺激相对应,听觉皮层中的 alpha 振幅相对增加。因此,数据表明,同步机制在限定的通带内运行,使得对于 subdelta 任务节律,会调用震荡谐波。这些 delta 同步振荡的相位调制 alpha 频带功率。这反过来可能分别增加或减少对相关和不相关刺激的反应性。
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