Yousem S A, Taylor S R
Department of Pathology, Presbyterian University Hospital, Pittsburgh, Pennsylvania.
Mod Pathol. 1990 Jul;3(4):502-7.
Twelve typical carcinoid tumors (TCT) and eight atypical (malignant) carcinoid tumors (ACT) of the lung were studied for quantitative DNA content by image analysis in order to identify prognostic features. No correlation of any histologic variables of the TCTs and ACTs with abnormal DNA content were noted. Furthermore, it was concluded that although abnormalities of DNA content, particularly aneuploidy, are common in ACTs, DNA ploidy cannot be used independently to assess malignant potential.
对12例肺典型类癌肿瘤（TCT）和8例非典型（恶性）类癌肿瘤（ACT）进行了图像分析定量DNA含量研究，以确定预后特征。未发现TCT和ACT的任何组织学变量与异常DNA含量相关。此外，得出的结论是，尽管DNA含量异常，尤其是非整倍体在ACT中很常见，但DNA倍体不能独立用于评估恶性潜能。
