Bascuñana Patricia, Pena Irene, Picazo Juan J, Velasco Aurelio C
Servicio de Microbiología Clínica, Hospital Clínico San Carlos, Madrid, Spain.
Rev Esp Quimioter. 2011 Dec;24(4):213-6.
C. jejuni as well as some hippurate-negative Campylobacter species and related diarrheagenic organisms, are the leading cause of gastroenteritis in our environment all throughout the year. The aim of the present study was to determine the sensitivity of hippurate-negative Campylobacter and Helicobacter pullorum strains isolated from the stools of patients with diarrhea. We tested 39 Campylobacter coli, two C. lari and five Helicobacter pullorum strains identified by mass spectrometry analysis. The sensitivity to amoxicillin-clavulanic acid, erytrhomycin, azithromycin, gentamicin, ciprofloxacin, levofloxacin, tetracycline, tigecycline and chloramphenicol was tested by E-test. Most hippurate-negative Campylobacter and H. pullorum isolates studied showed high resistance to tetracycline and to the two fluorquinolones tested. On the other side, all strains were sensitive to amoxicillin-clavulanic acid, tigecycline and chloramphenicol, while most of them were sensitive to both macrolides tested and to gentamicin.
空肠弯曲菌以及一些马尿酸盐阴性弯曲菌属物种和相关致泻性生物，是全年我们所处环境中肠胃炎的主要病因。本研究的目的是确定从腹泻患者粪便中分离出的马尿酸盐阴性弯曲菌和幽门螺杆菌菌株的敏感性。我们检测了通过质谱分析鉴定的39株大肠弯曲菌、2株海鸥弯曲菌和5株幽门螺杆菌菌株。通过E试验检测了对阿莫西林-克拉维酸、红霉素、阿奇霉素、庆大霉素、环丙沙星、左氧氟沙星、四环素、替加环素和氯霉素的敏感性。所研究的大多数马尿酸盐阴性弯曲菌和幽门螺杆菌分离株对四环素和所检测的两种氟喹诺酮类药物显示出高耐药性。另一方面，所有菌株对阿莫西林-克拉维酸、替加环素和氯霉素敏感，而它们中的大多数对所检测的两种大环内酯类药物和庆大霉素敏感。
