Zainuddin Laila Ruwaida Mohd, Isa Nurfirdaus, Muda Wan Manan Wan, Mohamed Hamid Jan
Nutrition Program, School of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia and Dietetic Program, Faculty of Medicine and Health Sciences, Universiti Sultan Zainal Abidin, Terengganu, Malaysia.
Int J Prev Med. 2011 Oct;2(4):229-37.
Metabolic syndrome can be diagnosed according to several different criteria such as the latest International Diabetes Federation (IDF), National Cholesterol Education Program Adult Treatment Program III (NCEP ATPIII), and World Health Organization (WHO). The objectives of this study were to determine the prevalence of metabolic syndrome and the concordance between the above mentioned definition, and hypertriglyceridemic-waist criteria.
This cross sectional study was done in Bachok, Malaysia and involved 298 respondents aged between 18 to 70 years. Multistage random sampling method was used to identify study locations while convenient random sampling method was applied to select individuals. Hypertriglyceridemic waist was defined from an internationally acceptable cut-off criterion. Kappa statistic (κ test) was used to determine the concordance between various definitions and hypertriglyceridemic-waist.
The prevalence of metabolic syndrome based on different definitions was 32.2% (IDF), 28.5% (NCEP ATP III) and 12.4% (modified WHO). The prevalence of hypertriglyceridemic-waist was 19.7% and based on the IDF criteria a total of 97.5% participants with hypertriglyceridemic-waist had metabolic syndrome. The IDF criteria showed the highest concordance with NCEP ATPIII criteria (κ = 0.63), followed by hypertriglyceridemic-waist criteria (κ = 0.62) and WHO criteria (κ = 0.26).
The prevalence of metabolic syndrome was highest using the IDF criteria compared to NCEP ATPIII, modified WHO and hypertriglyceridemic-waist. There was a good concordance of IDF criteria with NCEP ATP III and hypertriglyceridemic-waist criteria.
代谢综合征可依据多种不同标准进行诊断,如最新的国际糖尿病联盟(IDF)、美国国家胆固醇教育计划成人治疗组第三次报告(NCEP ATPIII)以及世界卫生组织(WHO)的标准。本研究的目的是确定代谢综合征的患病率,以及上述定义与高甘油三酯血症腰围标准之间的一致性。
这项横断面研究在马来西亚巴株巴辖进行,涉及298名年龄在18至70岁之间的受访者。采用多阶段随机抽样方法确定研究地点,同时运用方便随机抽样方法选取个体。高甘油三酯血症腰围依据国际认可的截断标准来定义。使用Kappa统计量(κ检验)来确定不同定义与高甘油三酯血症腰围之间的一致性。
基于不同定义的代谢综合征患病率分别为32.2%(IDF)、28.5%(NCEP ATP III)和12.4%(修订后的WHO)。高甘油三酯血症腰围的患病率为19.7%,根据IDF标准,共有97.5%的高甘油三酯血症腰围参与者患有代谢综合征。IDF标准与NCEP ATPIII标准的一致性最高(κ = 0.63),其次是高甘油三酯血症腰围标准(κ = 0.62),与WHO标准的一致性为(κ = 0.26)。
与NCEP ATPIII、修订后的WHO及高甘油三酯血症腰围标准相比,使用IDF标准时代谢综合征的患病率最高。IDF标准与NCEP ATP III以及高甘油三酯血症腰围标准具有良好的一致性。