a Psychology and Genetics Research Group , The Guy's, King's College, and St Thomas Hospitals' Medical and Dental School , Guy's Campus , London , SEI 9RT.
Psychol Health. 2000 Nov;14(6):1077-88. doi: 10.1080/08870440008407368.
Abstract An analogue study investigated the impact of genetic testing on perceptions of disease. Using a 2 × 2 design, participants (n = 212) imagined receiving the information that they were at increased risk for either heart disease or arthritis. The type of risk information was either genetic or unspecified. Presentation of genetic risk information resulted in the condition being perceived as less preventable. Causal models of disease where investigated using principal components analysis. When hem disease was the stimulus condition, attributions to genes and chance were positively associated following unspecified risk information, and negatively associated following genetic risk information. When arthritis was the stimulus condition, presentation of genetic risk information was associated with attributions to genes becoming separated from the other attributions. One explanation for this is that providing genetic risk information may decrease perceptions of a sense of randomness or uncertainty in disease causation. The extent to which these effects occur in clinical populations. and their behavioural consequences. needs to be established.
摘要 一项模拟研究调查了基因检测对疾病认知的影响。研究采用 2×2 设计，让 212 名参与者想象自己收到了有关心脏病或关节炎风险增加的信息。风险信息的类型要么是基因的，要么是非特定的。基因风险信息的呈现导致人们认为这种疾病更难预防。使用主成分分析研究了疾病的因果模型。当血液疾病是刺激条件时，在非特定风险信息下，归因于基因和机会呈正相关，而在遗传风险信息下呈负相关。当关节炎是刺激条件时，呈现基因风险信息与将基因归因与其他归因分开有关。对此的一种解释是，提供基因风险信息可能会降低人们对疾病病因中随机性或不确定性的感知。这些影响在临床人群中发生的程度及其行为后果需要确定。
