Unit of Maxillofacial Surgery, San Martino University Hospital, Via Largo R. Benzi n°10, Genoa, Italy.
Int J Oral Maxillofac Surg. 2012 Mar;41(3):321-3. doi: 10.1016/j.ijom.2011.11.010. Epub 2011 Dec 15.
Tenosynovial giant cell tumour (TGCT) is a rare benign proliferative disorder of the synovium characterised by destructive invasion by synovial-like mononuclear cells. Two variants have been distinguished: a localized (TGCT-L) and a diffuse (TGCT-D) type. TGCT usually affects adults with a peak incidence in the fifth and sixth decades of life and is more often seen in women than in men. One of the most common soft tissue tumours of the hand (finger joints and tendon sheaths), it is exceedingly uncommon in the head or neck. Only three cases of TGCT-D have been described in the literature. This report presents a case of TGCT-D in the temporomandibular joint.
腱鞘巨细胞瘤（TGCT）是一种罕见的良性滑膜增生性疾病，其特征为滑膜样单核细胞的破坏性浸润。已经区分出两种变体：局限性（TGCT-L）和弥漫性（TGCT-D）。TGCT 通常影响成年人，发病高峰期在第五和第六个十年，女性比男性更常见。它是手部（指间关节和腱鞘）最常见的软组织肿瘤之一，在头部或颈部极为罕见。文献中仅描述了三例 TGCT-D。本报告介绍了一例发生在颞下颌关节的 TGCT-D。
