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精索静脉曲张逆行栓塞术治疗青少年精索静脉曲张:一种有效的临床治疗选择。

Varicocele retrograde embolization with boiling contrast medium and gelatin sponges in adolescent subjects: a clinically effective therapeutic alternative.

机构信息

Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH 45229-3039, USA.

出版信息

J Vasc Interv Radiol. 2012 Feb;23(2):206-10. doi: 10.1016/j.jvir.2011.10.021. Epub 2011 Dec 15.

Abstract

PURPOSE

Varicoceles occur in approximately 15% of adolescent male subjects and may impair future fertility. The present study describes a varicocele treatment technique involving percutaneous retrograde embolization with boiling hot contrast medium and gelatin sponge pledgets.

MATERIALS AND METHODS

A retrospective review of medical records and imaging of all patients who underwent percutaneous retrograde varicocele embolization from 2005 to 2010 was performed. Pre- and postembolization symptoms, physical findings, and ultrasound findings were documented. Fifteen patients (16 embolizations) were identified, with an average age of 15.9 years (range, 12-18 y). Nine were referred because of persistent varicocele after surgical ligation. Three had grade 2 and nine had grade 3 varicoceles. Two had grade 1 varicoceles; one was painful and one was associated with poor semen quality. One varicocele was not clinically evident, but was associated with persistently decreased testicular size. Nine patients had pain or discomfort, and six had no discomfort. Clinical resolution was defined by a combination of symptom resolution and a lack of physical examination findings of varicocele or findings of treated varicocele.

RESULTS

Fifteen of the 16 embolizations (94%) were technically successful. Clinical resolution was documented in 14 of 15 patients (95%); one patient experienced a recurrence at 30 months, which was successfully reembolized. One patient experienced temporary paresthesia of the left thigh. There were no major postprocedural complications. Mean follow-up duration was 11 months.

CONCLUSIONS

Retrograde embolization of varicoceles in adolescent subjects with the use of boiling hot contrast medium and gelatin sponges is a promising technique that appears effective.

摘要

目的

精索静脉曲张在大约 15%的青春期男性中发生,可能会损害未来的生育能力。本研究描述了一种精索静脉曲张治疗技术,涉及使用过热的对比剂和明胶海绵颗粒进行经皮逆行栓塞。

材料和方法

对 2005 年至 2010 年期间接受经皮逆行精索静脉曲张栓塞的所有患者的病历和影像学进行回顾性分析。记录栓塞前和栓塞后的症状、体格检查发现和超声发现。共确定了 15 例患者(16 次栓塞),平均年龄为 15.9 岁(范围,12-18 岁)。9 例因手术后结扎后精索静脉曲张持续存在而转诊。3 例为 2 级精索静脉曲张,9 例为 3 级精索静脉曲张。2 例为 1 级精索静脉曲张;1 例为疼痛性精索静脉曲张,1 例与精液质量差有关。1 例精索静脉曲张在临床上并不明显,但与睾丸大小持续下降有关。9 例患者有疼痛或不适,6 例无不适。临床缓解定义为症状缓解和体检未发现精索静脉曲张或治疗后的精索静脉曲张。

结果

16 次栓塞中的 15 次(94%)技术上成功。15 例患者中的 14 例(95%)记录到临床缓解;1 例患者在 30 个月时复发,再次栓塞成功。1 例患者出现左大腿短暂感觉异常。无重大术后并发症。平均随访时间为 11 个月。

结论

使用过热的对比剂和明胶海绵颗粒对青少年精索静脉曲张患者进行逆行栓塞是一种很有前途的技术,似乎有效。

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