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经导管聚多卡醇泡沫硬化疗法治疗男性精索静脉曲张:关于替代技术的临床成功率、并发症及患者满意度评估

Treatment of male varicoceles by transcatheter polidocanol foam sclerotherapy: evaluation of clinical success, complications, and patients' satisfaction with regard to alternative techniques.

作者信息

Ali Alma, Wirth Stefan, Treitl Karla Maria, Treitl Marcus

机构信息

Institute for Clinical Radiology, Hospital of the Ludwig-Maximilians University of Munich, Nussbaumstr. 20, 80336, Munich, Germany,

出版信息

Eur Radiol. 2015 Oct;25(10):2889-97. doi: 10.1007/s00330-015-3684-5. Epub 2015 Mar 22.

Abstract

OBJECTIVES

We report our experience with polidocanol foam sclerotherapy with no additional coils, evaluating clinical success, patients' satisfaction, and complications.

METHODS

We conducted a retrospective study of 141 patients with 146 varicoceles (mean age: 29.3 years; range: 13 - 60 years) who underwent foam sclerotherapy with polidocanol 2% (range: 2 - 12 ml) in an outpatient setting between January 2007 and December 2013. For the follow-up, telephone interviews with the patients were conducted (mean follow-up time: 46.4 months, standard deviation: 20.17 months).

RESULTS

The technical success rate was 91.8%. There was a 55.8% response rate to the telephone interviews. Follow-up revealed a clinical success rate of 83.9% and a persistence or relapse rate of 16.1%. Of the patients, 81.9% were absolutely satisfied with the outcome. In 94.9% of cases, pain or discomfort resolution was reported, and in 97% of cases, aesthetic issues were no longer a problem. Of partners, 63.2% achieved pregnancy, and in 50% of patients with preprocedural testicular atrophy, catch-up growth was observed. One patient with pampiniform plexus phlebitis received inpatient treatment with no long-term damage recorded.

CONCLUSIONS

Polidocanol foam varicocele sclerotherapy is a safe and effective procedure, with a high rate of patients' satisfaction, clinical and technical success, and considerable catch-up growth and pregnancy achievement.

KEY POINTS

• Varicocele treatment using polidocanol foam sclerotherapy is a safe and effective procedure. • It is easily feasible in an outpatient setting. • The clinical and technical success rates are high. • It shows a high rate of patients' satisfaction and symptom resolution. • Postinterventional catch-up growth and pregnancy achievement are considerable.

摘要

目的

我们报告在不使用额外线圈的情况下聚多卡醇泡沫硬化疗法的经验,评估临床成功率、患者满意度及并发症。

方法

我们对2007年1月至2013年12月期间在门诊接受2%聚多卡醇(用量范围:2 - 12毫升)泡沫硬化疗法的141例患者(共146条精索静脉曲张)进行了一项回顾性研究。随访时,对患者进行了电话访谈(平均随访时间:46.4个月,标准差:20.17个月)。

结果

技术成功率为91.8%。电话访谈的回复率为55.8%。随访显示临床成功率为83.9%,持续存在或复发率为16.1%。患者中,81.9%对结果完全满意。94.9%的病例报告疼痛或不适得到缓解,97%的病例美观问题不再是困扰。伴侣中,63.2%成功受孕,在术前存在睾丸萎缩的患者中,50%观察到了追赶生长。1例患有精索静脉丛炎的患者接受了住院治疗,未记录到长期损害。

结论

聚多卡醇泡沫精索静脉曲张硬化疗法是一种安全有效的手术,患者满意度高,临床和技术成功率高,有显著的追赶生长和受孕成功率。

关键点

• 使用聚多卡醇泡沫硬化疗法治疗精索静脉曲张是一种安全有效的手术。• 在门诊环境中易于实施。• 临床和技术成功率高。• 患者满意度高且症状缓解率高。• 介入后追赶生长和受孕成功率显著。

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