Textile Engineering Department, Center of Excellence in Textile, Amirkabir University of Technology, Tehran, Iran.
Colloids Surf B Biointerfaces. 2012 Apr 1;92:9-15. doi: 10.1016/j.colsurfb.2011.10.062. Epub 2011 Nov 27.
Silver nanoparticles are being used increasingly in various applications because of their antibacterial properties. It is necessary to lower their direct contact with the skin by embedding in a polymer reducing their side effects. In this study, silver nanoparticles were synthesized inside the wool fibers acted as a polyfunctional ligands. Lecithin as a biological lipid was used to enhance the diffusion of silver ions and nanoparticles into the wool fibers reducing cytotoxicity effects of the nano silver loaded wool. The highest loading efficiency and inhibition zone was observed on the wool with the highest lecithin concentration. Presence of lecithin reduced the rate of nano silver release which results in decreasing the specific coefficient of lethality. Also, the extracted solution of the synthesized silver nanoparticles on the wool has not altered the morphology of L929 fibroblast cells.
由于银纳米粒子具有抗菌特性,因此它们在各种应用中被越来越多地使用。需要通过嵌入聚合物来降低它们与皮肤的直接接触,从而减少其副作用。在这项研究中,银纳米粒子在羊毛纤维内合成,充当多官能团配体。使用卵磷脂作为生物脂质来增强银离子和纳米粒子扩散到羊毛纤维中,从而降低负载纳米银的羊毛的细胞毒性作用。在卵磷脂浓度最高的羊毛上观察到最高的负载效率和抑菌圈。卵磷脂的存在降低了纳米银的释放速度,从而降低了致死率的特异性系数。此外,在羊毛上合成的银纳米粒子的提取溶液并未改变 L929 成纤维细胞的形态。