Jozefowiez Jeremie, Witnauer James E, Miller Ralph R
Université Charles de Gaulle-Lile3, France.
Behav Processes. 2012 Mar;89(3):239-43. doi: 10.1016/j.beproc.2011.12.002. Epub 2011 Dec 13.
The present study examined the temporal pattern of responding in a conditioned bar-press suppression task in rats. Rats were exposed to either a 30-s or a 120-s conditioned stimulus (CS) followed by a footshock. Training took place either while the rats were lever-pressing for water (online), or with the lever removed from the box (offline). They were then exposed to the CS while they were lever-pressing for water, either in the training context or in a different context. Bar-press suppression during the CS was constant across the duration of the CS during training, but was restricted to the initial portion of the CS at the time of testing, especially when subjects were tested in a different context. Those results replicate the reactive (as opposed to anticipatory) pattern observed in a lick suppression procedure by Jozefowiez et al. (2011) and indicate that a change in context at the time of testing might be critical for its expression.
本研究考察了大鼠条件性压杆抑制任务中的反应时间模式。大鼠接受30秒或120秒的条件刺激（CS），随后给予足部电击。训练在大鼠按压杠杆获取水时（在线）进行，或者将杠杆从实验箱中移除（离线）。然后，在它们按压杠杆获取水时，让它们在训练环境或不同环境中接受CS。CS期间的压杆抑制在训练期间CS的持续时间内是恒定的，但在测试时仅限于CS的初始部分，尤其是当在不同环境中对受试者进行测试时。这些结果重复了Jozefowiez等人（2011年）在舔舐抑制程序中观察到的反应性（而非预期性）模式，并表明测试时环境的变化可能对其表现至关重要。
