Nassaralla Belquiz Rodrigues do Amaral, Nassaralla Junior João Jorge
Goiânia Eye Institute, Department of Cornea and Refractive Surgery, Brazil.
Arq Bras Oftalmol. 2012 Jan-Feb;75(1):33-7.
To determine the ten-year visual results and outcomes of excimer laser phototherapeutic keratectomy (PTK) for recurrent corneal erosions.
Twenty-six eyes of 23 patients with recurrent corneal erosions were treated by PTK from 1996 to 2000 at the Goiania Eye Institute, Brazil. All eyes had failed to respond to conventional therapy. Data regarding preoperative and postoperative best-spectacle-corrected visual acuity (BSCVA), spherical equivalent (SE), symptomatic relief, incidence of recurrence, and complications arising from the laser treatment were analyzed. The mean duration of symptoms prior to PTK was 18 months (range, 8 to 36 months). The corneal epithelium was debrided, and laser ablation was performed to a depth of 5 micron with an ablation zone of 7 to 9 mm, using the Technolas 217C Plano Scan excimer laser. Mean postoperative follow-up was 12 years (range, 10 to 14 years).
At the last follow-up visit, 15 eyes (57.69%) were symptomsfree. Five eyes (19.2%) had occasional mild symptoms of irritation and photophobia upon awakening. Recurrence of painful corneal erosions occurred in six eyes (23.07%), which required a PTK retreatment. Twenty-four eyes had a preserved or improved BCVA, while 2 eyes showed deterioration of 1 line on Snellen test. Eleven eyes (42.3%) had no change in SE, and the others (57.69%) had a change of less than +/-0.75 diopters (D). There were no major complications during the follow-up period.
Ten-year data show that PTK is a safe, fast, effective and minimal invasive choice of treatment for recurrent corneal erosions in patients who do not respond to conventional treatments.
确定准分子激光光治疗性角膜切削术(PTK)治疗复发性角膜糜烂的十年视觉效果及预后。
1996年至2000年期间,巴西戈亚尼亚眼科研究所对23例复发性角膜糜烂患者的26只眼进行了PTK治疗。所有患眼对传统治疗均无反应。分析术前及术后最佳矫正视力(BSCVA)、等效球镜度(SE)、症状缓解情况、复发率以及激光治疗引起的并发症等数据。PTK治疗前症状的平均持续时间为18个月(范围8至36个月)。使用Technolas 217C Plano Scan准分子激光清除角膜上皮,并进行深度为5微米、消融区为7至9毫米的激光消融。术后平均随访12年(范围10至14年)。
在最后一次随访时,15只眼(57.69%)无症状。5只眼(19.2%)在晨起时偶尔有轻度刺激和畏光症状。6只眼(23.07%)发生了疼痛性角膜糜烂复发,需要再次进行PTK治疗。24只眼的BCVA保持或提高,2只眼在斯内伦视力表检查中视力下降1行。11只眼(42.3%)的SE无变化,其他眼(57.69%)的变化小于±0.75屈光度(D)。随访期间无重大并发症发生。
十年数据表明,对于对传统治疗无反应的复发性角膜糜烂患者,PTK是一种安全、快速、有效且微创的治疗选择。