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应用磁共振自旋标记技术对胰液流动进行可视化研究:正常和病理生理状态下的初步结果。

Visualization of pancreatic juice movement using unenhanced MR imaging with spin labeling: preliminary results in normal and pathophysiologic conditions.

机构信息

Sendai City Medical Center, Department of Radiology, Sendai, Japan.

出版信息

J Magn Reson Imaging. 2012 May;35(5):1119-24. doi: 10.1002/jmri.23533. Epub 2011 Dec 16.

DOI:10.1002/jmri.23533
PMID:22180260
Abstract

PURPOSE

To visualize the movement of pancreatic juice noninvasively by using an unenhanced magnetic resonance (MR) imaging technique.

MATERIALS AND METHODS

Institutional review board approval and informed consent were obtained for this study. A flow-out technique of time-spatial labeling inversion pulse (SLIP) technique was applied using both nonselective and selective inversion pulses to label, or tag, pancreatic juice to move out of the region. Ten normal (eight men, two women; age range, 22-61 years; mean age, 35 years) and two pathologic conditions were examined on a commercially available 1.5 Tesla MR imager with quadrature-detected phased-array coils. All images were evaluated by two radiologists to assess depiction of the pancreatic juice movement or pancreatic juice reflux as compared to the pancreatic duct or the common bile duct on MRCP obtained before time-SLIP examination.

RESULTS

The tagged pancreatic juice was satisfactory visualized after applying the pulse labeling. Noninvasive visualization of pancreatic juice movement, including normal pancreatic juice movement and reflux from the main pancreatic duct into the common bile duct, was possible by using the unenhanced time-SLIP technique.

CONCLUSION

Noninvasive visualization of pancreatic juice movement is possible by using the unenhanced MR imaging time-SLIP technique.

摘要

目的

利用非增强型磁共振成像(MR)技术无创可视化胰液流动。

材料与方法

本研究经机构审查委员会批准并获得患者知情同意。采用时间空间标记反转脉冲(SLIP)技术的流出技术,使用非选择性和选择性反转脉冲对胰液进行标记或标记,使其从区域中流出。在配备有正交检测相控阵线圈的商业上可用的 1.5TMR 成像仪上检查了 10 例正常(8 名男性,2 名女性;年龄范围,22-61 岁;平均年龄,35 岁)和 2 例病理状况。由两位放射科医生评估所有图像,以评估与胰管或胰胆管对比时对胰液流动或胰液反流的显示情况,在进行时间-SLIP 检查之前获得 MRCP。

结果

应用脉冲标记后,标记的胰液可得到满意显示。通过使用非增强型时间-SLIP 技术,可无创可视化胰液流动,包括正常胰液流动和主胰管内胰液反流至胆总管。

结论

使用非增强型磁共振成像时间-SLIP 技术可无创可视化胰液流动。

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