Department of Pediatrics, Sevket Yilmaz Education and Research Hospital, Bursa, Turkey.
Indian J Pediatr. 2012 Aug;79(8):1037-42. doi: 10.1007/s12098-011-0655-y. Epub 2011 Dec 17.
To determine the level and distribution of Cystatin C values in full-term and preterm healthy neonates for the purpose of diagnosis and follow-up of renal diseases of the neonates.
Eighty-eight newborn infants, including 55 preterm and 33 term born in the authors' hospital having no urinary tract pathology, symptoms or signs during prenatal and postnatal follow-up, were studied .
There were 25 neonates born between gestational wk of 28 and 32 (Group 1), 30 neonates born between gestational wk of 33-36 (Group 2) and 33 neonates born after gestational wk of 37 (Group 3). Average cystatin C values were determined to be 1.41 mg/l, 1.22 mg/l and 1.21 mg/l for Group 1, Group 2 and Group 3, respectively.
Evaluation of cystatin C can be effective for follow-up of renal pathologies, because it is not affected by gender, body weight and muscle mass and has a constant production rate.
测定足月和早产健康新生儿胱抑素 C 值的水平和分布，以便诊断和随访新生儿肾脏疾病。
研究了作者所在医院的 88 例新生儿，包括 55 例早产儿和 33 例足月出生的新生儿，他们在产前和产后随访期间均无尿路病理、症状或体征。
28 至 32 孕周（第 1 组）有 25 例新生儿，33-36 孕周（第 2 组）有 30 例新生儿，37 孕周后（第 3 组）有 33 例新生儿。第 1 组、第 2 组和第 3 组的平均胱抑素 C 值分别为 1.41mg/L、1.22mg/L 和 1.21mg/L。
胱抑素 C 的评估可有效随访肾脏疾病，因为它不受性别、体重和肌肉量的影响，且具有恒定的产生率。
