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机会性口腔病原体多聚糖普雷沃氏菌模式菌株(PPPA20)的非连续完成基因组序列

Non-contiguous finished genome sequence of the opportunistic oral pathogen Prevotella multisaccharivorax type strain (PPPA20).

作者信息

Pati Amrita, Gronow Sabine, Lu Megan, Lapidus Alla, Nolan Matt, Lucas Susan, Hammon Nancy, Deshpande Shweta, Cheng Jan-Fang, Tapia Roxanne, Han Cliff, Goodwin Lynne, Pitluck Sam, Liolios Konstantinos, Pagani Ioanna, Mavromatis Konstantinos, Mikhailova Natalia, Huntemann Marcel, Chen Amy, Palaniappan Krishna, Land Miriam, Hauser Loren, Detter John C, Brambilla Evelyne-Marie, Rohde Manfred, Göker Markus, Woyke Tanja, Bristow James, Eisen Jonathan A, Markowitz Victor, Hugenholtz Philip, Kyrpides Nikos C, Klenk Hans-Peter, Ivanova Natalia

出版信息

Stand Genomic Sci. 2011 Oct 15;5(1):41-9. doi: 10.4056/sigs.2164949. Epub 2011 Sep 23.

Abstract

Prevotella multisaccharivorax Sakamoto et al. 2005 is a species of the large genus Prevotella, which belongs to the family Prevotellaceae. The species is of medical interest because its members are able to cause diseases in the human oral cavity such as periodontitis, root caries and others. Although 77 Prevotella genomes have already been sequenced or are targeted for sequencing, this is only the second completed genome sequence of a type strain of a species within the genus Prevotella to be published. The 3,388,644 bp long genome is assembled in three non-contiguous contigs, harbors 2,876 protein-coding and 75 RNA genes and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

摘要

多聚糖普雷沃氏菌(坂本等人,2005年)是大型普雷沃氏菌属的一个物种,该菌属属于普雷沃氏菌科。该物种具有医学研究价值,因为其成员能够在人类口腔中引发诸如牙周炎、根龋等疾病。尽管已经有77个普雷沃氏菌基因组被测序或计划测序,但这是普雷沃氏菌属内已发表的第二个物种模式菌株的完整基因组序列。这个长度为3388644 bp的基因组由三个不连续的重叠群组装而成,包含2876个蛋白质编码基因和75个RNA基因,是细菌和古菌基因组百科全书项目的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b99e/3236051/4869f8064994/sigs.2164949-f1.jpg

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