Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
World Neurosurg. 2011 Dec;76(6 Suppl):S85-90. doi: 10.1016/j.wneu.2011.07.023.
Stroke remains one of the most devastating of all neurological diseases, often causing death or gross physical impairment or disability. As numerous countries throughout the world undergo the epidemiological transition of diseases, trends in the prevalence of stroke have dramatically changed.
All major international epidemiological articles published during the past 20 years addressing the global burden of stroke were reviewed. A focus was placed upon better defining current and future trends in surveillance, incidence, burden of disease, mortality, and costs associated with stroke internationally.
Despite the fact that various surveillance systems are used to identify stroke and its sequela around the world, it is clear that stroke remains one of the top causes of mortality and disability-adjusted life-years (DALYs) lost globally. Concerning trends include the increase of stroke mortality and lost DALYs in low- and middle-income countries. The global economic impact of stroke may be dire if effective preventive measures are not implemented to help decrease the burden of this disease.
The global burden of stroke is high, inclusive of increasing incidence, mortality, DALYs, and economic impact, particularly in low- and middle-income countries. The implementation of better surveillance systems and prevention programs are needed to help track current trends as well as to curb the projected exponential increase in stroke worldwide.
脑卒中是最具破坏性的神经疾病之一，常导致死亡或严重的身体损伤或残疾。随着世界上许多国家经历疾病的流行病学转变，脑卒中的流行趋势发生了显著变化。
综述了过去 20 年来所有主要的国际流行病学文章，这些文章都涉及全球脑卒中负担。重点是更好地定义国际上脑卒中的监测、发病率、疾病负担、死亡率和相关成本的当前和未来趋势。
尽管世界各地使用各种监测系统来识别和跟踪脑卒中及其后果，但脑卒中仍然是全球死亡率和伤残调整生命年（DALYs）损失的主要原因之一。相关趋势包括中低收入国家脑卒中死亡率和 DALYs 损失的增加。如果不实施有效的预防措施来帮助减轻这种疾病的负担，那么脑卒中的全球经济影响可能是严重的。
脑卒中的全球负担很高，包括发病率、死亡率、DALYs 和经济影响的增加，特别是在中低收入国家。需要实施更好的监测系统和预防计划，以帮助跟踪当前的趋势，并遏制全球脑卒中呈指数级增长的预测。
