Matérne Marie, Lindvall Mialinn Arvidsson, Appelros Peter, Eriksson Olivia, Jarl Gustav
School of Behavioural, Social and Legal Sciences, Örebro University, Örebro, Sweden.
School of Health, Care and Social Welfare, Mälardalen University, Västerås, Sweden.
BMC Neurol. 2025 Apr 23;25(1):177. doi: 10.1186/s12883-025-04143-2.
Post-stroke fatigue (PSF) is a common complication following stroke that affects approximately 50% of stroke survivors.
The purpose of this study was to investigate the role of comorbidities in PSF and the impact of PSF on Quality of Life (QoL). To achieve this, residual stroke symptoms have also been considered.
The participants were stroke survivors living in a Swedish municipality. Self-reported data were collected via the Fatigue Assessment Scale (FAS), the Riksstroke questionnaire, and the Short Form Health Survey 36 (SF-36). Linear multiple regression and Spearman's correlation coefficient were used to analyze the data.
A total of 142 participants (83 men) with a mean age of 74.8 (SD 9.7) years were included in the study. Fatigue levels were classified as normal (FAS 10-21) for 70 (49.3%) individuals, mild-to-moderate (FAS 22-34) for 56 (39.4%) individuals, and severe (FAS 35-50) for 16 (11.3%) individuals. The mean FAS score was 23.3 (SD 8.2). Multiple regression analysis indicated that the presence of vertigo (β = 0.24, p = 0.004), chronic pulmonary disorders (β = 0.29, p = 0.003), and hemiparesis (β = 0.18, p = 0.05) were associated with more severe PSF. The model explained 19.2% of the variance in PSF. A higher level of PSF was associated with worse QoL in all eight SF-36 domains (r = -0.38 to -0.67).
Vertigo, chronic pulmonary disorders, and hemiparesis were significantly associated with more severe PSF. Additionally, higher levels of fatigue were associated with a worse QoL. These findings confirm that PSF is a multifaceted phenomenon, underscoring the importance of addressing PSF in rehabilitation to improve outcomes for stroke survivors.
中风后疲劳（PSF）是中风后常见的并发症，约50%的中风幸存者会受到影响。
本研究旨在调查合并症在PSF中的作用以及PSF对生活质量（QoL）的影响。为实现这一目标，还考虑了残留的中风症状。
参与者为居住在瑞典一个市镇的中风幸存者。通过疲劳评估量表（FAS）、瑞典中风问卷和简短健康调查问卷36（SF - 36）收集自我报告的数据。采用线性多元回归和Spearman相关系数分析数据。
共有142名参与者（83名男性）纳入研究，平均年龄为74.8（标准差9.7）岁。疲劳水平分类为：70名（49.3%）个体为正常（FAS 10 - 21），56名（39.4%）个体为轻至中度（FAS 22 - 34），16名（11.3%）个体为重度（FAS 35 - 50）。FAS平均得分为23.3（标准差8.2）。多元回归分析表明，眩晕（β = 0.24，p = 0.004）、慢性肺部疾病（β = 0.29，p = 0.003）和偏瘫（β = 0.18，p = 0.05）与更严重的PSF相关。该模型解释了PSF中19.2%的方差。在所有八个SF - 36领域中，较高水平的PSF与较差的QoL相关（r = -0.38至 -0.67）。
眩晕、慢性肺部疾病和偏瘫与更严重的PSF显著相关。此外，更高水平的疲劳与更差的QoL相关。这些发现证实PSF是一个多方面的现象，强调了在康复中解决PSF以改善中风幸存者预后的重要性。
