Department of Pediatric Surgery, Hospital Universitario La Paz and Universidad Autonoma de Madrid, Madrid, Spain.
Scand J Surg. 2011;100(4):273-8. doi: 10.1177/145749691110000407.
Esophageal atresia (EA) with or without tracheo-esophageal fistula (TEF) is a rare condition that can be nowadays succesfully treated. The current interest therefore is focused on the management of the difficult cases, on thoracoscopic approach, and on some aspects of the long-term results.
The current strategies for the difficult or impossible anastomoses in pure and long-gap EA, the introduction of thoracoscopic repair and the causes, mechanisms and management of post-operative gastro-esophageal reflux (GER) are reviewed.
Methods of esophageal elongation and multi-staged repair of pure and long-gap EA allow anastomosis but with functional results that are often poor. Esophageal replacement with colon or stomach achieves at least similar results and often requires less procedures. Thoracoscopic repair is a promising adjunct, but the difficulties for setting it as a gold-standard are pointed out. GER is a part of the disease and its surgical treatment, that is often required, is burdened by high failure rates.
EA with or without TEF can be successfully treated in most cases, but a number of unsolved issues remain and the current approach to difficult cases will certainly evolve in the future.
食管闭锁(EA)伴或不伴气管食管瘘(TEF)是一种罕见的疾病,如今可以成功治疗。因此,目前的研究重点是处理困难病例、胸腔镜手术以及一些长期结果的方面。
本文回顾了治疗单纯型和长段型 EA 中困难或无法吻合的策略、胸腔镜修复的引入,以及术后胃食管反流(GER)的原因、机制和处理方法。
食管延长和多阶段修复单纯型和长段型 EA 的方法可以进行吻合,但功能结果往往较差。结肠或胃食管替代术可以达到至少相似的结果,并且通常需要更少的手术。胸腔镜修复是一种很有前途的辅助手段,但要将其确立为金标准仍存在困难。GER 是疾病的一部分,其手术治疗通常是必要的,但失败率很高。
大多数情况下可以成功治疗 EA 伴或不伴 TEF,但仍存在一些未解决的问题,目前对困难病例的处理方法在未来肯定会不断发展。