环孢素A联合治疗复发性皮下脂膜炎样T细胞淋巴瘤合并噬血细胞综合征。
Treatment relapsed subcutaneous panniculitis-like T-cell lymphoma together HPS by Cyclosporin A.
作者信息
Chen Ren'an, Liu Li, Liang Ying Min
机构信息
Department of Haematology, Tang du Hospital, Fourth Military Medical University, Xi'an, China.
出版信息
Hematol Rep. 2010 Jan 26;2(1):e9. doi: 10.4081/hr.2010.e9. Epub 2010 Nov 30.
Abstract
A 25-year-old man was diagnosised subcutaneous panniculitis-like T-cell lymphoma (SPTCL) through biopsy of a nodule from the anterior chest. After the treatment with prednisone 90 mg 3 weeks and tapered off in 1 month, the disease released, but relapsed together with symptions of hemophagocytic syndrome eight months after the termination of prednisone. CHOEP recipe was given but with unsatisfactory result until cyclosporine was prescribed. Cyclosporine was removed 6 months later. There is no evidence of clinical relapse 1 year later. This case suggest that cyclosporine could be a selectable treatment even in relapsed SPTCL.
摘要
一名25岁男性经前胸结节活检被诊断为皮下脂膜炎样T细胞淋巴瘤（SPTCL）。在用泼尼松90毫克治疗3周并在1个月内逐渐减量后，病情缓解，但在泼尼松停药8个月后复发并伴有噬血细胞综合征症状。给予CHOEP方案但效果不佳，直到开具环孢素。6个月后停用环孢素。1年后无临床复发证据。该病例表明，即使是复发的SPTCL，环孢素也可能是一种可选择的治疗方法。
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