铑（I）催化腈的碳-氰基键断裂的硼化反应。
Rhodium(I)-catalyzed borylation of nitriles through the cleavage of carbon-cyano bonds.
机构信息
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
出版信息
J Am Chem Soc. 2012 Jan 11;134(1):115-8. doi: 10.1021/ja2095975. Epub 2011 Dec 20.
PMID:22185487
Abstract
The reaction of aryl cyanides with diboron in the presence of a rhodium/Xantphos catalyst and DABCO affords arylboronic esters via carbon-cyano bond cleavage. This unprecedented mode of reactivity for a borylrhodium species allows the regioselective introduction of a boryl group in a late stage of synthesis.
摘要
芳基氰化物与二硼在铑/Xantphos 催化剂和 DABCO 的存在下反应，通过碳氰基键断裂生成芳基硼酸酯。这种铑硼酸物种前所未有的反应模式允许在合成的后期阶段进行区域选择性的硼基引入。
Zotero 插件