Department of Organic Chemistry, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague 6, Czech Republic.
Molecules. 2019 Sep 28;24(19):3523. doi: 10.3390/molecules24193523.
Indole derivatives are associated with a variety of both biological activities and applications in the field of material chemistry. A number of different strategies for synthesizing substituted indoles by means of the reactions of indolylboronic acids with electrophilic compounds are considered the methods of choice for modifying indoles because indolylboronic acids are easily available, stable, non-toxic and new reactions using indolylboronic acids have been described in the literature. Thus, the aim of this review is to summarize the methods available for the preparation of indolylboronic acids as well as their chemical transformations. The review covers the period 2010-2019.
吲哚衍生物具有广泛的生物活性和在材料化学领域的应用。通过吲哚硼酸与亲电化合物的反应来合成取代吲哚的许多不同策略被认为是修饰吲哚的首选方法，因为吲哚硼酸易得、稳定、无毒，并且文献中已经描述了使用吲哚硼酸的新反应。因此，本综述的目的是总结制备吲哚硼酸及其化学转化的方法。综述涵盖了 2010 年至 2019 年的时期。
