Pan American Health Organization, 525 23rd Street, NW, Washington, DC, USA.
Vaccine. 2011 Dec 30;29 Suppl 4:D91-6. doi: 10.1016/j.vaccine.2011.04.059. Epub 2011 Dec 18.
The challenge for regions embarking on measles elimination will be to maintain high population immunity with excellent vaccination coverage and high-quality surveillance. Meeting this challenge will be especially critical for dealing with importations of measles virus that will occur as long as the virus is circulating anywhere in the world. Implementation of measles elimination strategies will uncover the "hidden" disease burden of rubella and congenital rubella syndrome. As was the experience in countries of Latin America and the Caribbean (LAC), integrating the elimination of measles with the elimination of rubella will greatly enhance the capacity of countries to sustain progress in the reduction of measles mortality. Countries of LAC prioritized the routine national immunization program over short-term successes. While doing so, they have also encountered new opportunities to expand the benefits of disease control and elimination activities to other aspects of public health, most importantly towards improving health care for women and newborns and reducing inequities in health in the region's poorest communities. Implementation of similar strategies could lead to the global eradication of measles, rubella, and congenital rubella syndrome early this century, while strengthening routine immunization programs, and developing the capacity to introduce new and underutilized vaccines.
对于开始消除麻疹的地区来说,挑战将是在保持高人群免疫力、高疫苗接种覆盖率和高质量监测的情况下实现这一目标。应对麻疹病毒输入的挑战至关重要,只要病毒在世界任何地方传播,就会发生麻疹病毒输入的情况。实施消除麻疹策略将揭示风疹和先天性风疹综合征的“隐性”疾病负担。正如拉丁美洲和加勒比国家(LAC)的经验所表明的那样,将消除麻疹与消除风疹相结合,将极大地增强各国在降低麻疹死亡率方面取得进展的能力。LAC 国家优先考虑常规国家免疫规划,而不是短期的成功。在这样做的同时,他们还遇到了扩大疾病控制和消除活动效益的新机会,特别是在改善妇女和新生儿的医疗保健以及减少该地区最贫困社区的健康不平等方面。实施类似的策略可能导致本世纪初在全球消除麻疹、风疹和先天性风疹综合征,同时加强常规免疫规划,并发展引入新疫苗和利用不足疫苗的能力。