Int J Epidemiol. 2012 Feb;41(1):10-3. doi: 10.1093/ije/dyr184. Epub 2011 Dec 20.
The adult characteristics of animals, i.e. their phenotypes, must be studied in order to reach conclusions about the genotypes, i.e. the hereditary constitutions which form the basic subject-matter of genetics. But between genotype and phenotype lies a whole complex of development processes, for which Dr Waddington proposes the name 'epigenotype.' He here describes some of the general characteristics of an epigenotype, with special reference to the fruit-fly Drosophila melanogaster.
为了得出关于基因型的结论,即构成遗传学基本主题的遗传构成,必须研究动物的成年特征,即表型。但是,基因型和表型之间存在着一整套发育过程,为此,Waddington 博士提出了“表观基因型”这个名称。他在这里描述了表观基因型的一些一般特征,并特别提到了果蝇 Drosophila melanogaster。