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姜黄与葡萄糖酸氯己定漱口水预防牙菌斑形成和牙龈炎的比较评价:一项临床和微生物学研究。

Comparative evaluation of turmeric and chlorhexidine gluconate mouthwash in prevention of plaque formation and gingivitis: a clinical and microbiological study.

作者信息

Waghmare P F, Chaudhari A U, Karhadkar V M, Jamkhande A S

机构信息

Department of Periodontology, Bharati Vidyapeeth Deemed University, Dental College and Hospital, Pune Maharashtra, India.

出版信息

J Contemp Dent Pract. 2011 Jul 1;12(4):221-4. doi: 10.5005/jp-journals-10024-1038.

Abstract

AIM

To compare the efficacy of turmeric mouthwash and chlorhexidine gluconate mouthwash in prevention of gingivitis and plaque formation.

MATERIALS AND METHODS

A total of 100 randomly selected subjects visiting the Department of Periodontology at Bharati Vidyapeeth Deemed University, Dental College and Hospital, were considered for the study. The gingival index (GI) by Loe and Silness was recorded which was followed by Turesky- Gilmore-Glickman modification of Quigley Hein plaque index (TQHPI) at 0, 14 and 21 days. Individuals who gave an informed consent, subjects in the age group of 25 to 35 years with having fair and poor gingival index scores and a score >1 for plaque index, were included in the study.

RESULTS

Results showed statistically significant reduction (p < 0.05) in mean plaque index (PI) with chlorhexidine gluconate mouthwash when compared with turmeric mouthwash. No significant difference in mean gingival index (GI) was seen when chlorhexidine mouthwash was compared with turmeric mouthwash. Significant reduction in total microbial count (p < 0.05) was observed in both the groups. No significant difference was observed in total microbial count when chlorhexidine mouthwash was compared with turmeric mouthwash.

CONCLUSION

From the above observations, it can be concluded that chlorhexidine gluconate as well as turmeric mouthwash can be effectively used as an adjunct to mechanical plaque control methods in prevention of plaque and gingivitis. Chlorhexidine gluconate has been found to be more effective when antiplaque property was considered.

CLINICAL SIGNIFICANCE

From this study, it could be stated that turmeric is definitely a good adjunct to mechanical plaque control. Further studies are required on turmeric based mouthwash to establish it as a low cost plaque control measure.

摘要

目的

比较姜黄漱口水和葡萄糖酸洗必泰漱口水在预防牙龈炎和牙菌斑形成方面的疗效。

材料与方法

本研究共纳入100名随机选取的患者,他们均来自巴拉蒂维迪佩特被视为大学牙科学院和医院的牙周病科。记录Loe和Silness牙龈指数(GI),并在第0、14和21天采用Turesky - Gilmore - Glickman改良的Quigley Hein菌斑指数(TQHPI)。纳入研究的个体需签署知情同意书,年龄在25至35岁之间,牙龈指数评分中等及较差,且菌斑指数>1。

结果

结果显示,与姜黄漱口水相比,葡萄糖酸洗必泰漱口水的平均菌斑指数(PI)有统计学显著降低(p < 0.05)。将洗必泰漱口水与姜黄漱口水相比,平均牙龈指数(GI)未见显著差异。两组的总微生物计数均有显著降低(p < 0.05)。将洗必泰漱口水与姜黄漱口水相比,总微生物计数未见显著差异。

结论

从上述观察结果可以得出结论,葡萄糖酸洗必泰漱口水和姜黄漱口水均可有效用作机械性牙菌斑控制方法的辅助手段,以预防牙菌斑和牙龈炎。在抗牙菌斑性能方面,已发现葡萄糖酸洗必泰更有效。

临床意义

从本研究可以得出,姜黄绝对是机械性牙菌斑控制的良好辅助手段。需要对基于姜黄的漱口水进行进一步研究,以将其确立为一种低成本的牙菌斑控制措施。

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