Hüppi Petra S
Division of Development and Growth, Department of Pediatrics, Geneva University Hospitals, Geneva, Switzerland.
Top Magn Reson Imaging. 2011 Feb;22(1):33-8. doi: 10.1097/RMR.0b013e3182416f78.
Brain function is tightly linked to the development of the cortex. Until recently, assessing the human cortical development and folding was not possible in vivo. It is magnetic resonance imaging and new post-processing image analysis tools that have improved the understanding of cortical development. The combination of conventional magnetic resonance imaging and diffusion tensor imaging has further allowed depiction of the relationship of changes in intracortical layering and cortical folding. Being able to follow these early developmental processes has elucidated changes in early brain development due to changed environmental conditions in fetal life such as twinning and fetal growth restriction and postnatal conditions such as prematurity. This review further illustrates new data on brain structural asymmetries linked to the emergence of early language functions.
脑功能与皮质的发育紧密相连。直到最近，在活体状态下评估人类皮质发育和折叠情况仍是不可能的。正是磁共振成像和新的后处理图像分析工具改善了我们对皮质发育的理解。传统磁共振成像和扩散张量成像的结合进一步使得描绘皮质内分层变化与皮质折叠之间的关系成为可能。能够追踪这些早期发育过程已经阐明了由于胎儿期环境条件改变（如双胎妊娠和胎儿生长受限）以及出生后条件（如早产）导致的早期脑发育变化。本综述进一步阐述了与早期语言功能出现相关的脑结构不对称性的新数据。
