Dong Jing, Liu Baohua, Song Lei, Lu Lei, Xu Haitao, Gu Yue
Neurology Department, General Hospital, JiHa Group Company, Jilin, Jilin 10001, China.
Cell Tissue Bank. 2012 Dec;13(4):623-9. doi: 10.1007/s10561-011-9283-z. Epub 2011 Dec 21.
Neural stem cells functions as the pool of new neurons in adult brain, and plays important roles in normal brain function. Additionally, this pool reacts to brain ischemia, hemorrhage, trauma and many kinds of diseases, serving as endogenous repair mechanisms. The present manuscript discussed the responses of adult neurogenesis to brain ischemia and other insults, then the potential of neural stem cell transplantation therapy to treat such brain injury conditions.
神经干细胞作为成人大脑中新神经元的来源，在正常脑功能中发挥着重要作用。此外，这一细胞群对脑缺血、出血、创伤及多种疾病产生反应，作为内源性修复机制。本手稿讨论了成体神经发生对脑缺血及其他损伤的反应，以及神经干细胞移植治疗此类脑损伤情况的潜力。
