Barnavon Y, Wallack M K
Department of Surgery, Mount Sinai Medical Center, Miami Beach, Florid 33140.
Surg Gynecol Obstet. 1990 Oct;171(4):347-52.
The diagnosis of carcinoma of the breast during pregnancy poses a challenging dilemma. Although once regarded as incurable, recent reports reveal similar long term survival rates for pregnant and nonpregnant patients who have carcinoma of the breast. When referred to a surgeon, a pregnant woman with a suspicious mammary mass deserves an expedient histologic diagnosis; delay may jeopardize the chances of survival. Once the diagnosis is established, pregnant patients should be treated in a manner similar to nonpregnant patients because there is no evidence that carcinoma of the breast in pregnant women is biologically different than carcinoma of the breast in other premenopausal women. Fears of fetal exposure to radiation should not deter a physician from ordering appropriate preoperative diagnostic tests to stage the patients. Operation may be performed safely when general anesthesia is administered and postoperative adjuvant therapy should be administered when necessary. The involvement of multiple subspecialties in the management of these patients is highly recommended.
孕期乳腺癌的诊断是一个具有挑战性的难题。尽管曾经被认为无法治愈，但最近的报告显示，患有乳腺癌的孕妇和非孕妇的长期生存率相似。当转诊给外科医生时，患有可疑乳腺肿块的孕妇应尽快获得组织学诊断；延迟可能会危及生存机会。一旦确诊，孕妇应接受与非孕妇相似的治疗，因为没有证据表明孕妇乳腺癌在生物学上与其他绝经前女性的乳腺癌不同。对胎儿暴露于辐射的担忧不应阻止医生进行适当的术前诊断检查以对患者进行分期。在实施全身麻醉时可以安全地进行手术，必要时应给予术后辅助治疗。强烈建议多个亚专业参与这些患者的管理。
