餐后饱胀感与胃内容物快速流入十二指肠相关，而与慢性胃炎无关。
Postprandial fullness correlates with rapid inflow of gastric content into duodenum but not with chronic gastritis.
机构信息
Department of Gastroenterology, Graduate School of Medicine, University of Tokyo 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan.
出版信息
BMC Gastroenterol. 2011 Dec 21;11:140. doi: 10.1186/1471-230X-11-140.
BACKGROUND
The aim of this study is evaluating the correlation of postprandial fullness with chronic gastritis or rapid inflow of gastric content into duodenum, based on double-contrast barium X-ray imaging.
METHODS
253 healthy subjects who underwent upper gastrointestinal barium X-ray examination were analyzed. Chronic gastritis was judged from mucosal atrophy and hypertrophic thickened folds on barium X-ray images. For the gastric excretion, the tips of barium flow on the single-contrast frontal barium X-ray images of the stomach were classified into four categories; V type (all the barium remained in the stomach), V-H type (some barium had flowed into the duodenum but the tip of barium remained in the proximal half of the duodenal bulb), H-V type (some barium had flowed into the duodenum and the tip of barium was in the distal half of duodenal the bulb, but no barium was observed in the descending part of the duodenum), and H type (some barium had flowed into the descending part of the duodenum). The chi-square test and Cochran-Mantel-Haenzel test were used for evaluation.
RESULTS
Chronic gastritis was observed in 72 subjects, among which 21 subjects (29.2%) presented with postprandial fullness. For the remaining 181 subjects without chronic gastritis, 53 subjects (29.3%) complained of postprandial fullness. There is no significant correlation between chronic gastritis and postprandial fullness (p = 0.973). For the rapid flow of gastric content into duodenum, all the 253 subjects comprised 136 subjects with V type (in the stomach), 40 subjects with V-H type (in the proximal half of the duodenal bulb), 21 subjects with H-V type (in the distal half of the duodenal bulb), and 56 subjects with H type (in the descending part of the duodenum). Postprandial fullness was present in 30 subjects with V type (22.1%), 9 subjects with V-H type (22.5%), 8 subjects with H-V type (38.1%), and 27 subjects with H type (48.2%). There is a distinct correlation between postprandial fullness and gastric barium excretion on barium X-ray imaging (p = 0.002).
CONCLUSIONS
Bothersome postprandial fullness correlates with rapid inflow of gastric content into duodenum, but not with chronic gastritis.
背景
本研究旨在通过双对比钡餐 X 射线成像，评估餐后饱胀与慢性胃炎或胃内容物快速流入十二指肠之间的相关性。
方法
对 253 例接受上消化道钡餐 X 射线检查的健康受试者进行分析。慢性胃炎的判断依据为钡餐 X 射线图像上的黏膜萎缩和肥厚性皱襞。对于胃排空，胃单对比正位钡餐 X 射线图像上钡剂流的尖端分为 4 类；V 型（所有钡剂均留在胃内）、V-H 型（部分钡剂已流入十二指肠，但钡剂尖端仍留在十二指肠球部近端）、H-V 型（部分钡剂已流入十二指肠，钡剂尖端位于十二指肠球部远端，但降部无钡剂）和 H 型（部分钡剂已流入降部）。采用卡方检验和 Cochran-Mantel-Haenzel 检验进行评估。
结果
72 例受试者存在慢性胃炎，其中 21 例（29.2%）出现餐后饱胀。在其余 181 例无慢性胃炎的受试者中，53 例（29.3%）主诉餐后饱胀。慢性胃炎与餐后饱胀无显著相关性（p=0.973）。对于胃内容物快速流入十二指肠，253 例受试者均包括 136 例 V 型（胃内）、40 例 V-H 型（十二指肠球部近端）、21 例 H-V 型（十二指肠球部远端）和 56 例 H 型（降部）。V 型有 30 例（22.1%）、V-H 型 9 例（22.5%）、H-V 型 8 例（38.1%）和 H 型 27 例（48.2%）出现餐后饱胀。钡餐 X 射线成像上的餐后饱胀与胃钡剂排泄有明显相关性（p=0.002）。
结论
令人不适的餐后饱胀与胃内容物快速流入十二指肠有关，而与慢性胃炎无关。
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