Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, 1462 Clifton Road, Atlanta, GA 30322, USA.
Diabetes Res Clin Pract. 2012 Apr;96(1):76-83. doi: 10.1016/j.diabres.2011.11.014. Epub 2011 Dec 20.
To quantify relationships between societal-level factors and diabetes prevalence and identify potential policy responses.
Using data from International Diabetes Federation, World Health Organization, World Bank, and Food and Agricultural Organization, we extracted recent estimates for country-level variables: total caloric availability; sugar, animal fat, fruit and vegetable availability; physical inactivity markers (vehicles per capita and value-added from service sector); gross domestic product per capita (GDP); imports; and age-adjusted mortality rate. We used generalized linear models to investigate relationships between these factors and diabetes prevalence.
Median global diabetes prevalence was 6.4% in 2010. Every additional percentage point of calories from sugar/sweeteners and from animal fats were associated with 5% (OR: 1.05, 95% CI 1.02-1.07) and 3% (OR: 1.03, 95% CI 0.99-1.06) higher diabetes prevalence, respectively, while each additional unit in fruit and vegetable availability was associated with 3% lower diabetes prevalence (OR: 0.97, 95% CI 0.93-0.99). One percent higher GDP from the service industry was associated with a 1% higher diabetes prevalence (OR: 1.01, 95% CI 0.99-1.02).
Macro-level societal factors are associated with diabetes prevalence. Investigating how these factors affect individual-level diabetes risk may offer further insight into policy-level interventions.
量化社会层面因素与糖尿病患病率之间的关系,并确定潜在的政策应对措施。
我们利用国际糖尿病联合会、世界卫生组织、世界银行和粮农组织的数据,提取了国家层面变量的最新估计值:总热量供应;糖、动物脂肪、水果和蔬菜供应;身体活动指标(人均车辆和服务业附加值);人均国内生产总值(GDP);进口;以及年龄调整死亡率。我们使用广义线性模型来研究这些因素与糖尿病患病率之间的关系。
2010 年全球糖尿病患病率中位数为 6.4%。糖/甜味剂和动物脂肪提供的卡路里每增加 1%,糖尿病患病率分别增加 5%(OR:1.05,95%CI 1.02-1.07)和 3%(OR:1.03,95%CI 0.99-1.06),而水果和蔬菜供应量每增加一个单位,糖尿病患病率则降低 3%(OR:0.97,95%CI 0.93-0.99)。服务业 GDP 每增加 1%,糖尿病患病率就会增加 1%(OR:1.01,95%CI 0.99-1.02)。
宏观社会因素与糖尿病患病率有关。研究这些因素如何影响个体层面的糖尿病风险可能为政策层面的干预措施提供进一步的见解。