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体育活动对 1 型糖尿病有哪些健康益处?文献综述。

What are the health benefits of physical activity in type 1 diabetes mellitus? A literature review.

机构信息

Institute of Biomedical Research, School of Clinical and Experimental Medicine, University of Birmingham, Wolfson Drive, Birmingham B15 2TT, UK.

出版信息

Diabetologia. 2012 Mar;55(3):542-51. doi: 10.1007/s00125-011-2403-2. Epub 2011 Dec 22.

DOI:10.1007/s00125-011-2403-2
PMID:22189486
Abstract

Physical activity improves well-being and reduces the risk of heart disease, cancer and type 2 diabetes mellitus in the general population. In individuals with established type 2 diabetes, physical activity improves glucose and lipid levels, reduces weight and improves insulin resistance. In type 1 diabetes mellitus, however, the benefits of physical activity are less clear. There is poor evidence for a beneficial effect of physical activity on glycaemic control and microvascular complications, and significant risk of harm through hypoglycaemia. Here we review the literature relating to physical activity and health in type 1 diabetes. We examine its effect on a number of outcomes, including glycaemic control, lipids, blood pressure, diabetic complications, well-being and overall mortality. We conclude that whilst there is sufficient evidence to recommend physical activity in the management of type 1 diabetes, it is still unclear as to what form, duration and intensity should be recommended and whether there is benefit for many of the outcomes examined.

摘要

身体活动可改善整体人群的健康水平并降低心脏病、癌症和 2 型糖尿病的风险。在已确诊患有 2 型糖尿病的个体中,身体活动可改善血糖和血脂水平、减轻体重并改善胰岛素抵抗。然而,身体活动对 1 型糖尿病的益处尚不清楚。目前几乎没有证据表明身体活动对血糖控制和微血管并发症有有益影响,且低血糖的发生风险很大。在此,我们对 1 型糖尿病患者的身体活动与健康相关文献进行了综述。我们考察了身体活动对多种结局的影响,包括血糖控制、血脂、血压、糖尿病并发症、健康状况和总体死亡率。我们的结论是,虽然有充分的证据支持将身体活动作为 1 型糖尿病管理的一部分,但对于应该推荐何种类型、时长和强度的身体活动,以及对于许多所考察的结局是否有益,目前仍不明确。

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本文引用的文献

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Effect of exercise on albuminuria in people with diabetes.运动对糖尿病患者蛋白尿的影响。
Nephrology (Carlton). 2011 Nov;16(8):704-9. doi: 10.1111/j.1440-1797.2011.01508.x.
2
Effect of exercise intensity on albuminuria in adolescents with Type 1 diabetes mellitus.运动强度对 1 型糖尿病青少年白蛋白尿的影响。
Diabet Med. 2012 Jan;29(1):70-3. doi: 10.1111/j.1464-5491.2011.03380.x.
3
Lowering physical activity impairs glycemic control in healthy volunteers.体力活动减少会损害健康志愿者的血糖控制。
评估Diactive-1的可用性:用于1型糖尿病儿童和青少年个性化运动与教育的移动健康应用
Mhealth. 2025 Mar 10;11:16. doi: 10.21037/mhealth-24-63. eCollection 2025.
4
Management and Medical Care for Individuals with Type 1 Diabetes Running a Marathon.1型糖尿病患者马拉松参赛的管理与医疗护理
J Clin Med. 2025 Apr 6;14(7):2493. doi: 10.3390/jcm14072493.
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Brown and Beige Adipose Tissue: One or Different Targets for Treatment of Obesity and Obesity-Related Metabolic Disorders?棕色脂肪组织和米色脂肪组织:治疗肥胖及肥胖相关代谢紊乱的同一靶点还是不同靶点?
Int J Mol Sci. 2024 Dec 11;25(24):13295. doi: 10.3390/ijms252413295.
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The associations between dairy product intake, fatigue status, and physical activity among postpartum women in Saudi Arabia: a cross-sectional study.沙特阿拉伯产后女性乳制品摄入、疲劳状况和身体活动之间的关联:一项横断面研究。
BMC Public Health. 2024 Oct 9;24(1):2759. doi: 10.1186/s12889-024-20294-2.
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Diabetes Metab Syndr Obes. 2024 Sep 17;17:3491-3498. doi: 10.2147/DMSO.S474202. eCollection 2024.
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EXTOD-Immune: a randomised controlled trial to investigate whether a remotely monitored, home-based exercise intervention can reduce disease activity in people with type 1 diabetes.EXTOD-免疫:一项随机对照试验,旨在研究远程监测的居家运动干预是否能降低1型糖尿病患者的疾病活动度。
BMJ Open Sport Exerc Med. 2024 Aug 30;10(3):e002144. doi: 10.1136/bmjsem-2024-002144. eCollection 2024.
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JMIR Diabetes. 2024 Jul 30;9:e51491. doi: 10.2196/51491.
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Assessing the influence of insulin type (ultra-rapid vs rapid insulin) and exercise timing on postprandial exercise-induced hypoglycaemia risk in individuals with type 1 diabetes: a randomised controlled trial.评估胰岛素类型(超短效与短效胰岛素)和运动时机对 1 型糖尿病个体餐后运动诱发低血糖风险的影响:一项随机对照试验。
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JAMA. 2010 Nov 24;304(20):2253-62. doi: 10.1001/jama.2010.1710.
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Is exercise a therapeutic tool for improvement of cardiovascular risk factors in adolescents with type 1 diabetes mellitus? A randomised controlled trial.运动是否是改善 1 型糖尿病青少年心血管风险因素的治疗工具?一项随机对照试验。
Diabetol Metab Syndr. 2010 Jul 11;2(1):47. doi: 10.1186/1758-5996-2-47.