Departments of General Surgery, Mersin, Turkey.
Clinics (Sao Paulo). 2011;66(12):2001-5. doi: 10.1590/s1807-59322011001200001.
This prospective randomized clinical study was conducted to evaluate the safety and tolerability of early oral feeding after colorectal operations.
A total of 199 patients underwent colorectal surgery and were randomly assigned to early feeding (n = 99) or a regular diet (n = 100). Patients' characteristics, diagnoses, surgical procedures, comorbidity, bowel movements, defecation, nasogastric tube reinsertion, time of tolerance of solid diet, complications, and length of hospitalization were assessed.
The two groups were similar in terms of gender, age, diagnosis, surgical procedures, and comorbidity. In the early feeding group, 85.9% of patients tolerated the early feeding schedule. Bowel movements (1.7±0.89 vs. 3.27±1.3), defecation (3.4±0.77 vs. 4.38±1.18) and time of tolerance of solid diet (2.48±0.85 vs. 4.77±1.81) were significantly earlier in the early feeding group. There was no change between the groups in terms of nasogastric tube reinsertion, overall complication or anastomotic leakage. Hospitalization (5.55±2.35 vs. 9.0±6.5) was shorter in the early feeding group.
The present study indicated that early oral feeding after elective colorectal surgery was not only well tolerated by patients but also affected the postoperative outcomes positively. Early postoperative feeding is safe and leads to the early recovery of gastrointestinal functions.
本前瞻性随机临床试验旨在评估结直肠手术后早期口服喂养的安全性和耐受性。
共有 199 例接受结直肠手术的患者被随机分为早期喂养组(n = 99)和常规饮食组(n = 100)。评估患者的特征、诊断、手术程序、合并症、排便、排便、鼻胃管重新插入、固体饮食耐受时间、并发症和住院时间。
两组在性别、年龄、诊断、手术程序和合并症方面相似。在早期喂养组中,85.9%的患者耐受了早期喂养计划。早期喂养组的排便次数(1.7±0.89 比 3.27±1.3)、排便时间(3.4±0.77 比 4.38±1.18)和固体饮食耐受时间(2.48±0.85 比 4.77±1.81)均明显早于常规饮食组。两组之间在鼻胃管重新插入、总并发症或吻合口漏方面无差异。早期喂养组的住院时间(5.55±2.35 比 9.0±6.5)较短。
本研究表明,择期结直肠手术后早期口服喂养不仅患者耐受良好,而且对术后结局有积极影响。早期术后喂养是安全的,并导致胃肠道功能的早期恢复。