First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Clin Microbiol Infect. 2012 Feb;18(2):E16-9. doi: 10.1111/j.1469-0691.2011.03718.x. Epub 2011 Dec 22.
To estimate endemic areas for Crimean-Congo haemorrhagic fever (CCHF) in Greece, a country-wide seroepidemiological study was conducted, and 1611 human sera were prospectively collected along with data regarding possible risk factors for acquisition of infection, and tested for CCHF virus IgG antibodies by ELISA. The overall seroprevalence was 4.2%, with significant differences among prefectures, ranging from 0 to 27.5%. Multivariate analysis revealed that slaughtering and agricultural activities were significant risk factors for CCHFV seropositivity. The significantly high seroprevalence in specific prefectures, together with the extremely low number of CCHF cases, suggest that this phenomenon might be strain-related.
为了评估希腊克里米亚-刚果出血热（CCHF）的流行地区，进行了一项全国范围的血清流行病学研究，前瞻性采集了 1611 份人血清，并收集了可能感染的相关风险因素的数据，采用 ELISA 法检测 CCHF 病毒 IgG 抗体。总血清阳性率为 4.2%，不同州之间存在显著差异，范围为 0 至 27.5%。多因素分析显示，屠宰和农业活动是 CCHFV 血清阳性的显著危险因素。特定州的血清阳性率显著较高，而 CCHF 病例的数量极低，表明这种现象可能与菌株有关。
