First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Clin Microbiol Infect. 2010 Jul;16(7):843-7. doi: 10.1111/j.1469-0691.2009.02996.x. Epub 2009 Oct 19.
In the summer of 2008, the first case of Crimean-Congo haemorrhagic fever (CCHF) was observed in Greece. The laboratory diagnosis was established using nested RT-PCR and quantitative real-time RT-PCR. A high viral load and increased levels of cytokines were detected on the third day of illness and the patient died 7 days after the onset of symptoms. Nucleotide sequence analysis revealed that the Greek CCHF virus strain had high sequence identity with other Balkan CCHF virus strains.
2008 年夏，希腊出现首例克里米亚-刚果出血热（CCHF）病例。实验室诊断采用巢式 RT-PCR 和实时定量 RT-PCR。发病第 3 天即检测到高病毒载量和细胞因子水平升高，患者于症状出现后 7 天死亡。核苷酸序列分析显示，希腊 CCHF 病毒株与其他巴尔干半岛 CCHF 病毒株具有高度序列同源性。
