Bcl-3 在实体瘤中的作用。
Role of Bcl-3 in solid tumors.
机构信息
Instituto Nacional de Cancerología, Mexico City, Mexico.
出版信息
Mol Cancer. 2011 Dec 23;10:152. doi: 10.1186/1476-4598-10-152.
Abstract
Bcl-3 is an established oncogene in hematologic malignancies, such as B-cell chronic lymphocytic leukemias. Nevertheless, recent research has shown that it also participates in progression of diverse solid tumors. The present review summarizes the current knowledge of Bcl3 role in solid tumors progression, including some new insights in its possible molecular mechanisms of action.
摘要
Bcl-3 是血液恶性肿瘤（如 B 细胞慢性淋巴细胞白血病）中的一种既定癌基因。然而，最近的研究表明，它也参与了多种实体肿瘤的进展。本文综述总结了 Bcl3 在实体肿瘤进展中的作用的现有知识，包括其可能的作用机制的一些新见解。
Zotero 插件