St Georges Hospital, London, United Kingdom.
Early Hum Dev. 2012 Jan;88(1):15-9. doi: 10.1016/j.earlhumdev.2011.11.006.
Fetal intervention encompasses a range of procedures on the fetus with congenital structural anomalies, whilst still on the placental circulation. The concept of fetal surgery was conceived in order to prevent fetal or early postnatal death, or to prevent permanent irreversible organ damage. The benefit of these procedures has to be balanced with risks to both the mother and the fetus. Open fetal surgery, more commonly conducted in North American centres, involves open surgery to the uterus in order to operate on the fetus. Fetal intervention centres in Europe more commonly use minimally invasive fetoscopic surgery. This paper elaborates on the various strategies used in dealing with anomalies of different organ systems of the fetus.
胎儿干预涵盖了一系列针对先天性结构畸形胎儿的胎盘循环期的操作。胎儿手术的概念是为了预防胎儿或新生儿早期死亡,或预防永久性不可逆转的器官损伤。这些操作的益处必须与母婴风险相平衡。开放性胎儿手术,更常见于北美中心,需要对子宫进行开放性手术以对胎儿进行操作。欧洲的胎儿干预中心更常采用微创胎儿镜手术。本文详细阐述了处理不同器官系统胎儿畸形的各种策略。