Zelenková J, Toman R, Bielaszewská M, Hanika J, Zeman V
I. Interní klinika fakulty dĕtského lékarství Univerzity Karlovy, Praha.
Vnitr Lek. 1990 Jun;36(6):573-9.
The authors subjected to endoscopic examination 90 patients with duodenal ulcers. From each patient they collected a bioptic specimen of the gastric antrum and duodenal bulbus for microbiological and histological examination. They found that for detection of C. pylori the microscopic examination was most useful. The presence of C. pylori in the gastric antrum was detected in 87% of the subjects and in the duodenal bulb only in 48%. The difference is significant at the 0.01 level. To 43 patients of the group Ranitidine was administered. The ulcer was cured within 4 weeks in 35 subjects. Ranitidine did not affect the presence of C. pylori and antral gastritis. After cure of the ulcer the authors administered Tarivid to 10 patients with persisting C. pylori positivity. The presence of C. pylori and antral gastritis were not affected by this treatment.
作者对90例十二指肠溃疡患者进行了内镜检查。他们从每位患者身上采集了胃窦和十二指肠球部的活检标本，用于微生物学和组织学检查。他们发现，对于检测幽门螺杆菌，显微镜检查最为有用。87%的受试者胃窦中检测到幽门螺杆菌，而十二指肠球部仅48%检测到。差异在0.01水平具有显著性。给该组中的43例患者服用雷尼替丁。35例受试者的溃疡在4周内愈合。雷尼替丁不影响幽门螺杆菌的存在和胃窦胃炎。溃疡治愈后，作者给10例幽门螺杆菌持续阳性的患者服用泰胃美。这种治疗不影响幽门螺杆菌的存在和胃窦胃炎。
