Jerant-Patić V, Ziramov J, Vujkov V, Hrnjaković-Cvijetković I, Popović S
Medicinski Fakultet, Novi Sad.
Vojnosanit Pregl. 1990 May-Jun;47(3):167-72.
The results of the prospective study of chlamydia trachomatis infection in women are presented. The study comprised 288 women aged from 19 to 67 years with the completed clinical and anamnestic data and the following tests have been performed: indirect immunofluorescence test for detection of Chlamydia trachomatis antigens in endocervical smears (using monoclonal antibodies), ELISA test for detection of IgG antibodies against Chlamydia trachomatis in the sera and complement binding reaction for detection of antibodies against grouped Chlamydia antigen. Chlamydia trachomatis infection was found in 29.51% of cases equally distributed in all age groups. The incidence of Chlamydia positive findings was analysed according to clinical diagnosis, parity, relevant data from gynecologic anamnesis and the results of vaginal secretion and Papanicolau's stain test. In order to establish a reliable diagnosis of Chlamydia trachomatis infection two methods should be regularly used: one direct-for detection of a causative agent in patients' materials, and the other-indirect, for detection of specific antibodies in the serum.
本文展示了一项关于女性沙眼衣原体感染的前瞻性研究结果。该研究纳入了288名年龄在19岁至67岁之间的女性，她们均有完整的临床和既往病史资料，并进行了以下检测：采用间接免疫荧光试验（使用单克隆抗体）检测宫颈涂片中的沙眼衣原体抗原；采用酶联免疫吸附试验检测血清中抗沙眼衣原体IgG抗体；采用补体结合反应检测抗沙眼衣原体属抗原的抗体。在所有年龄组中，29.51%的病例发现有沙眼衣原体感染。根据临床诊断、产次、妇科既往病史相关数据以及阴道分泌物和巴氏染色试验结果，分析了衣原体阳性结果的发生率。为了建立可靠的沙眼衣原体感染诊断，应定期使用两种方法：一种是直接法，用于检测患者样本中的病原体；另一种是间接法，用于检测血清中的特异性抗体。
